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Pediatric brainstem abscess successfully treated with stereotactic aspiration: illustrative case
Journal article   Open access

Pediatric brainstem abscess successfully treated with stereotactic aspiration: illustrative case

Nahom Teferi, Ajmain Chowdhury, Sarah Lee, Meron Challa, Lukasz Weiner, Sarah Auerbach, Mahil Rao and Brian J. Dlouhy
Journal of Neurosurgery: Case Lessons, Vol.6(6), CASE23262
08/07/2023
DOI: 10.3171/CASE23262
PMCID: PMC10555595
PMID: 37581585
url
https://doi.org/10.3171/CASE23262View
Published (Version of record) Open Access

Abstract

BACKGROUND Pediatric brainstem abscesses are rare entities that account for 1% of all brain abscesses and, when diagnosed, constitute a neurosurgical emergency. OBSERVATIONS A previously healthy 11-year-old male presented with several days of worsening headache, confusion, and ataxia. Brain magnetic resonance imaging (MRI) revealed a midbrain and pons lesion. The patient subsequently had a rapid neurological decline with loss of consciousness and brainstem function. Follow-up MRI revealed significant enlargement of the brainstem lesion with extension into the pons, midbrain, and thalamus, with greater concerns for an abscess rather than a tumor or an inflammatory process. He was taken for an emergent stereotactic aspiration of the abscess, and broad-spectrum antibiotics were initiated. He had neurological improvement, which subsequently declined 5 days later with brain MRI revealing an increase in the brainstem abscess, which required a second stereotactic aspiration. After rehabilitation, he made a significant neurological recovery. LESSONS Pediatric brainstem abscesses are rare pathologies, and a high index of suspicion is needed in patients presenting with a brainstem lesion mimicking tumor but with rapid neurological decline despite no other evidence of infection or infectious/inflammatory markers. Stereotactic aspiration is required for large lesions to target the antibiotic treatment and as an adjunct to broad-spectrum antibiotics.

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