Journal article
Pediatric characteristics and the dose of propofol for sedation during radiological examinations: a retrospective analysis
Journal of international medical research, Vol.49(2), pp.030006052199099-300060521990992
02/01/2021
DOI: 10.1177/0300060521990992
PMCID: PMC7923994
PMID: 33641471
Abstract
Objective
The present study aimed to investigate patients' characteristics that can affect the dose of propofol required to sedate children undergoing imaging.
Methods
In this retrospective, observational study, we reviewed medical records of children aged 0 to 18 years who were classified as having American Society of Anesthesiologists status 1 or 2 and they underwent imaging under propofol sedation between January 2011 and August 2016. Collected data included patients' demographics, propofol doses, duration of sedation, and complications. Regression analysis was performed to determine patients' characteristics that may affect the dose of propofol required to induce sedation.
Results
A total of 925 patients were included. Simple linear regression showed that the dose of propofol was correlated with age, height, weight, and body surface area. Using the results of multiple linear regression, the following formula was used to estimate the dose of propofol (mg) for sedation: 0.75 + 0.14 x age (months) + 45.82 x body surface area (m(2)).
Conclusion
A child's age, height, and body surface area should be considered when deciding the induction dose of propofol. Additionally, the formula that we have proposed can be used to estimate the dose of propofol required to induce sedation in children undergoing imaging.
Details
- Title: Subtitle
- Pediatric characteristics and the dose of propofol for sedation during radiological examinations: a retrospective analysis
- Creators
- Ji Young Min - Catholic University of KoreaJeong-Rim Lee - Yonsei UniversityYhen Seoung Kang - Natl Insurance Serv Ilsan Hosp, Dept Anesthesiol & Pain Med, Anesthesia & Pain Res Inst, Ilsan, South KoreaJung Hwan Ho - Natl Insurance Serv Ilsan Hosp, Dept Anesthesiol & Pain Med, Anesthesia & Pain Res Inst, Ilsan, South KoreaHyo Jin Byon - Yonsei University
- Resource Type
- Journal article
- Publication Details
- Journal of international medical research, Vol.49(2), pp.030006052199099-300060521990992
- DOI
- 10.1177/0300060521990992
- PMID
- 33641471
- PMCID
- PMC7923994
- NLM abbreviation
- J Int Med Res
- ISSN
- 0300-0605
- eISSN
- 1473-2300
- Publisher
- Sage
- Number of pages
- 9
- Grant note
- HI16C0793 / Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) - Ministry of Health & Welfare, Republic of Korea
- Language
- English
- Date published
- 02/01/2021
- Academic Unit
- Anesthesia
- Record Identifier
- 9984806509502771
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