Journal article
Pediatric eosinophilic gastritis treated with benralizumab: A case report
JPGN reports, Vol.5(3), pp.394-397
08/13/2024
DOI: 10.1002/jpr3.12088
PMCID: PMC11322020
PMID: 39149169
Appears in UI Libraries Support Open Access
Abstract
We report one of the first cases of eosinophilic gastritis (EoG) in a child under 12 years treated with benralizumab. At 7 years, our patient was started on benralizumab after failing to respond to various combinations of high‐dose omeprazole, milk elimination diet, oral viscous budesonide, and oral systemic steroids. He had a complete depletion of gastrointestinal tissue eosinophils with improved symptoms but had symptomatic flares with tapering of background therapy. However, after 4 years on benralizumab he became symptomatic again. Benralizumab may be a viable option for EoG refractory to systemic steroids but only as a short‐term adjunct therapy. More robust studies with long‐term data are needed, especially in this younger population.
Details
- Title: Subtitle
- Pediatric eosinophilic gastritis treated with benralizumab: A case report
- Creators
- Donna Cheung - University of IowaDawn Ebach - University of IowaBenjamin Davis - University of Iowa
- Resource Type
- Journal article
- Publication Details
- JPGN reports, Vol.5(3), pp.394-397
- Publisher
- Wiley
- DOI
- 10.1002/jpr3.12088
- PMID
- 39149169
- PMCID
- PMC11322020
- ISSN
- 2691-171X
- eISSN
- 2691-171X
- Language
- English
- Electronic publication date
- 06/14/2024
- Date published
- 08/13/2024
- Academic Unit
- Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition; Immunology; Internal Medicine
- Record Identifier
- 9984648573102771
Metrics
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