Pediatric meningiomas: 65-year experience at a single institution

Andrew J Grossbach; Kelly B Mahaney; Arnold H Menezes

doi:10.3171/2017.2.PEDS16497

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Pediatric meningiomas: 65-year experience at a single institution

Journal article

Peer reviewed

Pediatric meningiomas: 65-year experience at a single institution

Andrew J Grossbach, Kelly B Mahaney and Arnold H Menezes

Journal of neurosurgery. Pediatrics, Vol.20(1), pp.42-50

07/2017

DOI: 10.3171/2017.2.PEDS16497

PMID: 28474981

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Abstract

OBJECTIVE Meningiomas are relatively common, typically benign neoplasms in adults; however, they are relatively rare in the pediatric population. Pediatric meningiomas behave very differently from their adult counterparts, tending to have more malignant histological subtypes and recur more frequently. The authors of this paper investigate the risk factors, pathological subtypes, and recurrence rates of pediatric meningiomas. METHODS A retrospective chart review was conducted at the University of Iowa to identify patients 20 years old and younger with meningiomas in the period from 1948 to 2015. RESULTS Sixty-seven meningiomas in 39 patients were identified. Eight patients had neurofibromatosis, 2 had a family history of meningioma, and 3 had prior radiation exposure. Twelve (31%) of the 39 patients had WHO Grade II or III lesions, and 15 (38%) had recurrent lesions after resection. CONCLUSIONS Pediatric meningiomas should be considered for early treatment and diligent follow-up.

Meningeal Neoplasms - epidemiology

Humans

Neoplasm Recurrence, Local - therapy

Risk Factors

Child, Preschool

Infant

Male

Meningeal Neoplasms - therapy

Meningioma - therapy

Neoplasm Recurrence, Local - pathology

Young Adult

Disease-Free Survival

Meningioma - pathology

Meningioma - epidemiology

Adolescent

Female

Neoplasm Recurrence, Local - epidemiology

Retrospective Studies

Meningeal Neoplasms - pathology

Child

Details

Title: Subtitle: Pediatric meningiomas: 65-year experience at a single institution
Creators: Andrew J Grossbach - Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa; and
Kelly B Mahaney - Department of Neurosurgery, University of Virginia, Charlottesville, Virginia
Arnold H Menezes - Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa; and
Resource Type: Journal article
Publication Details: Journal of neurosurgery. Pediatrics, Vol.20(1), pp.42-50
DOI: 10.3171/2017.2.PEDS16497
PMID: 28474981
NLM abbreviation: J Neurosurg Pediatr
ISSN: 1933-0707
eISSN: 1933-0715
Publisher: United States
Language: English
Date published: 07/2017
Academic Unit: Stead Family Department of Pediatrics; Neurosurgery; Otolaryngology
Record Identifier: 9984040236502771

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