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Pemphigus‐like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5‐year‐old girl
Journal article   Peer reviewed

Pemphigus‐like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5‐year‐old girl

Connie S. Zhong, Maria Trinidad Hasbun, Krystal M. Jones, Birgitta A.R. Schmidt and Sadaf H. Hussain
Pediatric dermatology, Vol.37(2), pp.379-380
03/2020
DOI: 10.1111/pde.14115
PMID: 32027759

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Abstract

Pemphigus and pemphigus‐like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus‐like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through a unique pathway, separate from the classic antibody‐mediated pathway. Our patient had a full recovery without recurrence after cessation of the inciting drug.
drug reaction imiquimod pemphigus‐like reaction

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