Journal article
Perceived effects of cannabis: Generalizability of changes in driving performance
Traffic injury prevention, Vol.23(S1), pp.S8-S13
10/10/2022
DOI: 10.1080/15389588.2022.2128787
PMID: 36622373
Abstract
The objective of this analysis was to determine the generalizability of the relationship between different samples of a driver's perceived state after cannabis use and related performance while operating a motor vehicle.
Data were collected from 52 subjects in a study examining the effects of cannabis on driving performance. Data were analyzed using the SAS GLM Select procedure, using stepwise selection, with subjective effects, dosing condition (placebo vs. 6.18% delta-9-tetrahydrocannabinol [THC]), and driving context as independent measures. Correlation matrices of measures of driving performance against subjective responses and dosing condition used Pearson's and Spearman's test statistics, respectively. Results were compared to a prior study from a sample of 10 subjects.
Subjective perceptions of acute cannabis impairment remain significant predictors of driving performance and explain individual variability in driving performance degradation as well as the data, beyond that which can be explained by acute use of cannabis alone. However, the significant subjective predictors of driving performance differ between the current and prior studies. To better understand these differences, correlations between subjective effects and performance measures were evaluated, which revealed that most correlations matched directionally (e.g., an increase in "good drug effect" was correlated with an increase in standard deviation of lane position [SDLP]). When there was a mismatch, 1 or more correlations were insignificant. Dosing condition and "stoned" were perfectly consistent; "high" and "sedated" contained 1 mismatch; and "anxious," "good drug effect" and "restless" contained 3 or more mismatches.
The results indicate that across both studies, differences in the perceived effects of cannabis are reflected in changes in both lateral and longitudinal control beyond the acute effects of cannabis, which may help explain individual variability in response to acute intoxication. However, the generalizability of these findings is lacking, as shown by inconsistencies in when and where subjective effects were significant. Other factors such as frequency of use, usage type, the evolving profile of a cannabis user, as well as other individual differences should be considered to explain this additional variability.
Details
- Title: Subtitle
- Perceived effects of cannabis: Generalizability of changes in driving performance
- Creators
- Thomas S. Burt - University of IowaTimothy L. Brown - University of IowaRose Schmitt - University of IowaDaniel McGehee - University of IowaGary Milavetz - University of IowaGary Gaffney - Roy J. and Lucille A. Carver College of MedicineChris Berka - Advanced Brain Monitoring
- Resource Type
- Journal article
- Publication Details
- Traffic injury prevention, Vol.23(S1), pp.S8-S13
- DOI
- 10.1080/15389588.2022.2128787
- PMID
- 36622373
- NLM abbreviation
- Traffic Inj Prev
- ISSN
- 1538-9588
- eISSN
- 1538-957X
- Publisher
- Taylor & Francis
- Grant note
- DOI: 10.13039/100000026, name: National Institute on Drug Abuse; name: IRB, award: 201911551; DOI: 10.13039/100006108, name: National Center for Advancing Translational Sciences and National Institutes of Health, award: U54TR001356
- Language
- English
- Date published
- 10/10/2022
- Academic Unit
- Pharmacy; Psychiatry; Occupational and Environmental Health; Iowa Technology Institute; Emergency Medicine; Pharmaceutical Sciences and Experimental Therapeutics; Driving Safety Research Institute; Industrial and Systems Engineering; Pharmacy Practice and Science; Center for Social Science Innovation; Injury Prevention Research Center; Public Policy Center (Archive)
- Record Identifier
- 9984366030702771
Metrics
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