Journal article
Perceptions and behaviours of infectious diseases physicians when managing urinary tract infections due to MDR organisms
Journal of antimicrobial chemotherapy, Vol.70(12), pp.3397-3400
12/2015
DOI: 10.1093/jac/dkv271
PMCID: PMC4652686
PMID: 26349519
Abstract
The objective of this study was to attain a better understanding of infectious diseases (ID) physicians' experience with MDR organism (MDRO) urinary tract infections (UTIs) by means of a survey on disease perception, diagnostic management and treatment preferences.
A nine-question survey was developed and distributed to members of the North American Emerging Infections Network (EIN) in September 2013.
Seven hundred and fourteen out of 1461 EIN members responded to the survey (49%). The responses of 603 responders were studied. Most providers perceived an increase in the incidence of MDRO UTIs over the past 3 years (75% of adult ID responders and 63% of paediatric ID responders). One hundred and thirty-four (22%) responders prefer intravenous over oral administration of antimicrobials when both are available, 171 (28%) prefer longer durations of therapy when comparing an MDRO with a susceptible isolate of the same species and 142 (24%) order a repeat urine culture as 'proof of cure' after treating an MDRO UTI. Nevertheless, 530 (88%) responders perceived MDRO UTIs to be of similar severity as non-MDRO UTIs. Fifty-five percent of providers prescribed fosfomycin for MDRO UTI at least once; the most common prescribing pattern (among a wide spectrum of approaches) was a single dose (16%).
Future studies on MDRO UTIs should clarify the role of resistance in patient outcomes and the comparative efficacy of different antimicrobials. Of particular interest is fosfomycin, which is unrelated to other antibiotic classes and may take a more prominent role in treating MDRO cystitis.
Details
- Title: Subtitle
- Perceptions and behaviours of infectious diseases physicians when managing urinary tract infections due to MDR organisms
- Creators
- Sergio E Trevino - Washington University in St. LouisHilary M Babcock - Washington University in St. LouisJeffrey P Henderson - Washington University in St. LouisMichael A Lane - Washington University in St. LouisSusan E Beekmann - University of IowaPhilip M Polgreen - University of IowaJonas Marschall - Division of Infectious Diseases, Washington University School of Medicine, 660 S. Euclid, St Louis, MO 63110, USA Department of Infectious Diseases, Inselspital, Bern University Hospital, Friedbühlstrasse 51, Bern 3010, Switzerland
- Resource Type
- Journal article
- Publication Details
- Journal of antimicrobial chemotherapy, Vol.70(12), pp.3397-3400
- DOI
- 10.1093/jac/dkv271
- PMID
- 26349519
- PMCID
- PMC4652686
- NLM abbreviation
- J Antimicrob Chemother
- ISSN
- 1460-2091
- eISSN
- 1460-2091
- Grant note
- KL2 TR000450 / NCATS NIH HHS R01 DK099534 / NIDDK NIH HHS TL1 TR000449 / NCATS NIH HHS UL1 TR000448 / NCATS NIH HHS
- Language
- English
- Date published
- 12/2015
- Academic Unit
- Infectious Diseases; Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984359885802771
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