Journal article
Percutaneous Closure of the Patent Ductus Arteriosus in Infants ≤2 kg: IMPACT Registry insights
Pediatrics (Evanston), Vol.152(3), e2023061460
09/2023
DOI: 10.1542/peds.2023-061460
PMID: 37529882
Abstract
Objectives: Percutaneous patent ductus arteriosus (PDA) closure is becoming the standard of care for definitive closure in progressively smaller and younger neonates. The objective of this study was to assess safety and feasibility of percutaneous PDA closure in patients ≤2 kg.
Methods: This was a cohort study using the IMPACT Registry (Improving Pediatric and Adult Congenital Treatments) from the American College of Cardiology Foundation's National Cardiovascular Data Registry. Patients who were ≤2 kg at the time of percutaneous PDA closure were included. The primary outcome was the composite of technical failure and/or major adverse event.
Results: A total of 1587 attempted PDA closures were included, with a 3% incidence of technical failure and 5.5% incidence of the composite outcome. Major adverse events were observed in 3.8% of the patients; the most common events were device embolization requiring retrieval and unplanned cardiac or vascular surgery in 1.3% and 1.3% of cases, respectively. The incidence of the composite outcome was associated with the need for arterial access (P < .001) as well as annual hospital volume of percutaneous PDA closures in infants ≤2 kg (P = .001). The incidence of the composite outcome has decreased overtime, whereas median weight at the time of procedure has also diminished.
Conclusions: Percutaneous PDA closure appears to be safe and feasible procedures in infants ≤2 kg. The incidence of major adverse events has continued to decline over the years and seems to have a strong correlation with individual center case volumes and expertise.
Details
- Title: Subtitle
- Percutaneous Closure of the Patent Ductus Arteriosus in Infants ≤2 kg: IMPACT Registry insights
- Creators
- Adrianne Rahde BischoffKevin F KennedyCarl H BackesShyam SathanandamPatrick J McNamara
- Resource Type
- Journal article
- Publication Details
- Pediatrics (Evanston), Vol.152(3), e2023061460
- DOI
- 10.1542/peds.2023-061460
- PMID
- 37529882
- NLM abbreviation
- Pediatrics
- eISSN
- 1098-4275
- Language
- English
- Electronic publication date
- 08/02/2023
- Date published
- 09/2023
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984447960202771
Metrics
19 Record Views