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Percutaneous closure of patent foramen ovale for treatment of hypoxemia: A case series and physiology review
Journal article   Open access   Peer reviewed

Percutaneous closure of patent foramen ovale for treatment of hypoxemia: A case series and physiology review

Jared Robl, Wasawat Vutthikraivit, Phillip Horwitz and Sidakpal Panaich
Catheterization and cardiovascular interventions, Vol.100(3), pp.471-475
09/01/2022
DOI: 10.1002/ccd.30317
PMCID: PMC9540543
PMID: 35758238
url
https://doi.org/10.1002/ccd.30317View
Published (Version of record)CC BY-NC-ND V4.0 Open Access

Abstract

Intracardiac right‐to‐left shunt (RTLS) mediated hypoxemia is a rare complication of patent foramen ovale (PFO). The process may be potentiated by reversal of the usual trans‐atrial pressure gradient, or from alteration of intracardiac geometry such that venous flow is preferentially directed toward the PFO. We describe a series of four patients who presented with hypoxemia, detailing the diagnostic evaluation which led to the ascertainment of intracardiac RTLS across PFO as the culprit pathology. All underwent successful percutaneous closure with rapid resolution of hypoxemia. Particular attention is given to the underlying anatomic and physiologic derangements facilitating the intracardiac RTLS.
intracardiac shunt platypnea‐orthodeoxia syndrome UIOWA OA Agreement

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