Journal article
Percutaneous patent foramen ovale and atrial septal defect closure in adults: Results and device comparison in 100 consecutive implants at a single center
Catheterization and Cardiovascular Interventions, Vol.45(4), pp.197-203
02/2005
DOI: 10.1002/ccd.20260
PMID: 15678448
Abstract
Closure of interatrial septal defects with percutaneous devices is increasingly common. However, the indications for closure and techniques for device implantation are diverse. We reviewed our first 100 consecutive implants to assess and compare the indications, results, complications, and evolution of techniques for percutaneous patent foramen ovale (PFO) and atrial septal defect (ASD) closure. The mean age of patients was 52 years and 70% were female. Paradoxical embolism was the predominant indication (94%) for PFO closure and significant left-to-right shunt was the most frequent indication (89%) for ASD closure. Implantation success was 94% with major complications in 3 patients (2.8%). Transesophageal echocardiography was utilized in the initial 27 procedures and then replaced by intracardiac echocardiography in subsequent ones, with an associated reduction in procedure and physician time. During 6 months of follow-up, 3 patients were readmitted for atrial arrhythmias (2 patients) and an MRI-negative neurologic event (1 patient). Echocardiography at 6 months in 83% of the PFO patients revealed moderate and severe positive contrast studies for right-to-left shunting in one third of patients, with differences between devices and insertion techniques. This single-center experience with percutaneous device closure of PFO and ASD in adults demonstrates excellent results with few complications.
Details
- Title: Subtitle
- Percutaneous patent foramen ovale and atrial septal defect closure in adults: Results and device comparison in 100 consecutive implants at a single center
- Creators
- Howard C Herrmann - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaFrank E Silvestry - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaRuchira Glaser - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaVincent See - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaScott Kasner - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaDanielle Bradbury - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaGene Chang - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaJohn W Hirshfeld Jr - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaPhillip A Horwitz - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, PennsylvaniaMichael Kelly - Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
- Resource Type
- Journal article
- Publication Details
- Catheterization and Cardiovascular Interventions, Vol.45(4), pp.197-203
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/ccd.20260
- PMID
- 15678448
- ISSN
- 1522-1946
- eISSN
- 1097-0304
- Number of pages
- 7
- Language
- English
- Date published
- 02/2005
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094669002771
Metrics
14 Record Views