Journal article
Perfusion imaging in acute ischemic stroke: let us improve the science before changing clinical practice
Radiology, Vol.266(1), pp.16-21
01/2013
DOI: 10.1148/radiol.12112134
PMID: 23264523
Abstract
Reperfusion is the only proved effective therapy for patients with acute ischemic stroke (1). There is an urgent need for improvement in acute stroke care, as only 15%–20% of patients, at best, are eligible for intravenous tissue plasminogen activator (tPA), and many patients so treated do not achieve good clinical outcome (2,3). This need has resulted in an enormous amount of research about developing better methods of revascularization and neuroprotection and designing better imaging paradigms for patient selection. A key element of these advanced imaging paradigms is perfusion imaging.
We intend to bring focus on the extent of our current knowledge on the imaging triaging of acute ischemic stroke patients by using perfusion imaging and to make recommendations for practice and clinical research. Our position is that perfusion imaging should not be used outside of clinical studies seeking to establish the utility of these measurements. We do not intend to focus on the utility of perfusion imaging in other relevant clinical scenarios where this imaging modality has defined its role, and neither do we intend to go into detail on the mathematic constructs behind these techniques.
Details
- Title: Subtitle
- Perfusion imaging in acute ischemic stroke: let us improve the science before changing clinical practice
- Creators
- Mayank Goyal - Department of Radiology and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada. mgoyal@ucalgary.caBijoy K MenonColin P Derdeyn
- Resource Type
- Journal article
- Publication Details
- Radiology, Vol.266(1), pp.16-21
- Publisher
- United States
- DOI
- 10.1148/radiol.12112134
- PMID
- 23264523
- ISSN
- 0033-8419
- eISSN
- 1527-1315
- Language
- English
- Date published
- 01/2013
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020609502771
Metrics
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