Peri-implantitis and systemic inflammation: A critical update

Nasser M. Assery; Carlos A. Jurado; Mansour K. Assery; Kelvin I. Afrashtehfar

doi:10.1016/j.sdentj.2023.04.005

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Peri-implantitis and systemic inflammation: A critical update

Journal article

Open access

Peri-implantitis and systemic inflammation: A critical update

Nasser M. Assery, Carlos A. Jurado, Mansour K. Assery and Kelvin I. Afrashtehfar

The Saudi dental journal, Vol.35(5), pp.443-450

07/2023

DOI: 10.1016/j.sdentj.2023.04.005

PMCID: PMC10373087

PMID: 37520600

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https://doi.org/10.1016/j.sdentj.2023.04.005View

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Abstract

Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, including uncontrolled diabetes mellitus, psychological stress, cardiovascular disease, obesity, and infectious diseases such as COVID-19. As an inflammatory disease, peri-implantitis may trigger systemic inflammation by elevating circulating levels of pro-inflammatory cytokines, which could have unknown impacts on overall health. While the relationship between periodontal health and systemic conditions is better understood, the association between peri-implant disease and systemic inflammation remains unclear. Therefore, this comprehensive review aims to summarize the most recent evidence on the relationship between peri-implantitis and systemic inflammation, focusing on biological complications, microbiology, and biomarkers. This review aims to enhance our understanding of the links between peri-implantitis and systemic inflammation and promote further research in this field by discussing the latest insights and clinical implications.

Biomarkers

Cardiovascular Disease

Inflammation

Microbiology

Biological complications

Dental implants

Peri-implantitis

Systemic disease

Details

Title: Subtitle: Peri-implantitis and systemic inflammation: A critical update
Creators: Nasser M. Assery - University of Rochester
Carlos A. Jurado - University of Iowa
Mansour K. Assery - Riyadh Elm University
Kelvin I. Afrashtehfar - Ajman University
Resource Type: Journal article
Publication Details: The Saudi dental journal, Vol.35(5), pp.443-450
DOI: 10.1016/j.sdentj.2023.04.005
PMID: 37520600
PMCID: PMC10373087
NLM abbreviation: Saudi Dent J
ISSN: 1013-9052
eISSN: 1658-3558
Publisher: Elsevier B.V
Language: English
Electronic publication date: 05/07/2023
Date published: 07/2023
Academic Unit: Prosthodontics
Record Identifier: 9984413066802771

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