Journal article
Periapical Inflammation and Bacterial Penetration After Coronal Inoculation of Dog Roots Filled With RealSeal 1 or Thermafil
Journal of Endodontics, Vol.35(6), pp.852-857
2009
DOI: 10.1016/j.joen.2009.03.050
PMID: 19482185
Abstract
The purpose of this study was to subject 2 carrier-based root filling products to a 4-month microbial challenge in a dog model with histologic markers to assess periapical inflammation and bacterial penetration of the 2 filling materials. Histologic evidence of bacterial penetration and periapical inflammation were the outcome parameters used to compare the products. Teeth were aseptically prepared and then filled with carrier-based Resilon (RealSeal 1 [RS-1], n = 25) or with carrier-based gutta-percha (Thermafil, n = 25) and were left exposed for 4 months. The first control group received a coronal seal over either RS-1 or Thermafil root fillings (n = 8). A second control group was instrumented and left completely empty (n = 8). Histologic evidence of periapical inflammation was observed in 29% of the Thermafil group and in 9% of the RS-1 group. This difference was only significant when controlling for a possible tooth position effect on inflammation presence ( P < .05). Histologic evidence of bacterial penetration was present in 9% of the RS-1 group and in 70% of the Thermafil group. The difference in penetration rates between RS-1 and Thermafil was statistically significant when controlling for any dog or tooth position effects on bacterial penetration ( P < .001). Furthermore, there was a statistically significant correlation between histologic evidence of inflammation and histologic evidence of infection ( P = .002). RS-1 appeared to resist bacterial penetration more effectively than Thermafil under the conditions of this study.
Details
- Title: Subtitle
- Periapical Inflammation and Bacterial Penetration After Coronal Inoculation of Dog Roots Filled With RealSeal 1 or Thermafil
- Creators
- Derek Duggan - Department of Endodontics, University of North Carolina at Chapel Hill, Chapel Hill, North CarolinaRoland R Arnold - Department of Diagnostic Sciences & General Dentistry Dental Research, University of North Carolina at Chapel Hill, Chapel Hill, North CarolinaFabricio B Teixeira - Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, TexasDaniel J Caplan - Department of Preventive and Community Dentistry, University of Iowa College of Dentistry, Iowa City, IowaPeter Tawil - Department of Endodontics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
- Resource Type
- Journal article
- Publication Details
- Journal of Endodontics, Vol.35(6), pp.852-857
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.joen.2009.03.050
- PMID
- 19482185
- ISSN
- 0099-2399
- eISSN
- 1878-3554
- Language
- English
- Date published
- 2009
- Academic Unit
- Preventive and Community Dentistry; Endodontics
- Record Identifier
- 9983917656702771
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