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Pericardial sarcoma
Journal article   Peer reviewed

Pericardial sarcoma

Mahmoud Abdelnaby, Abdallah Almaghraby, Yehia Saleh and Rasha Abayazeed
BMJ case reports, Vol.2018, p.bcr-2018-226112
10/07/2018
DOI: 10.1136/bcr-2018-226112
PMCID: PMC6194453
PMID: 30297493
url
https://www.ncbi.nlm.nih.gov/pmc/articles/6194453View
Open Access

Abstract

Pericardial sarcomas are extremely rare aggressive neoplasms. Non-specific symptoms and incidental discovery are usually the rule. Multimodality imaging is extremely important for diagnosis and tissue characterisation of all cardiac masses. Despite treatment, pericardial sarcomas are considered extremely fatal. We encountered a 27-year-old female patient who presented to our facility with progressive dyspnoea. On examination, clinical signs of cardiac tamponade were appreciated, transthoracic echocardiography revealed a tamponading pericardial effusion and a large heterogeneous pericardial mass. Pericardiocentesis revealed haemorrhagic fluid. Subsequently, CT revealed a pericardial mass compressing the right atrium. Excision biopsy showed a well-circumscribed mass, and cut sections showed friable grey–white tissue with areas of haemorrhage and necrosis. Pathological examination confirmed the diagnosis of high-grade undifferentiated sarcoma of the pericardium. The patient was started on adjuvant chemotherapy and radiotherapy. Follow-up after 1 year showed no relapse.

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