Peripheral quantitative computed tomography : Measurement sensitivity in persons with and without spinal cord injury

Richard K SHIELDS; Shauna DUDLEY-JAVOROSKI; Kathryn M BOALDIN; Trent A COREY; Daniel B FOG; Jacquelyn M RUEN

doi:10.1016/j.apmr.2006.07.257

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Peripheral quantitative computed tomography : Measurement sensitivity in persons with and without spinal cord injury

Journal article

Peer reviewed

Peripheral quantitative computed tomography : Measurement sensitivity in persons with and without spinal cord injury

Richard K SHIELDS, Shauna DUDLEY-JAVOROSKI, Kathryn M BOALDIN, Trent A COREY, Daniel B FOG and Jacquelyn M RUEN

Archives of physical medicine and rehabilitation, Vol.87(10), pp.1376-1381

2006

DOI: 10.1016/j.apmr.2006.07.257

PMCID: PMC3272268

PMID: 17023249

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Abstract

Objectives: To determine (1) the error attributable to external tibia-length measurements by using peripheral quantitative computed tomography (pQCT) and (2) the effect these errors have on scan location and tibia trabecular bone mineral density (BMD) after spinal cord injury (SCI). Design: Blinded comparison and criterion standard in matched cohorts. Setting: Primary care university hospital. Participants: Eight able-bodied subjects underwent tibia length measurement. A separate cohort of 7 men with SCI and 7 able-bodied age-matched male controls underwent pQCT analysis. Interventions: Not applicable. Main outcome measures: The projected worst-case tibia-length-measurement error translated into a pQCT slice placement error of +/-3 mm. We collected pQCT slices at the distal 4% tibia site, 3 mm proximal and 3 mm distal to that site, and then quantified BMD error attributable to slice placement. Results: Absolute BMD error was greater for able-bodied than for SCI subjects (5.87 mg/cm(3) vs 4.5 mg/cm(3)). However, the percentage error in BMD was larger for SCI than able-bodied subjects (4.56% vs 2.23%). Conclusions: During cross-sectional studies of various populations, BMD differences up to 5% may be attributable to variation in limb-length-measurement error.

Neurology

Osteoporosis. Osteomalacia. Paget disease

Miscellaneous

Cerebrospinal fluid. Meninges. Spinal cord

Diseases of the osteoarticular system

Biological and medical sciences

Medical sciences

Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)

Nervous system (semeiology, syndromes)

Details

Title: Subtitle: Peripheral quantitative computed tomography : Measurement sensitivity in persons with and without spinal cord injury
Creators: Richard K SHIELDS - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Shauna DUDLEY-JAVOROSKI - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Kathryn M BOALDIN - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Trent A COREY - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Daniel B FOG - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Jacquelyn M RUEN - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States
Resource Type: Journal article
Publication Details: Archives of physical medicine and rehabilitation, Vol.87(10), pp.1376-1381
DOI: 10.1016/j.apmr.2006.07.257
PMID: 17023249
PMCID: PMC3272268
NLM abbreviation: Arch Phys Med Rehabil
ISSN: 0003-9993
eISSN: 1532-821X
Publisher: Elsevier; New York, NY
Language: English
Date published: 2006
Academic Unit: Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
Record Identifier: 9984047648802771

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