Journal article
Perspective on emergence and re-emergence of amantadine resistant influenza A viruses in domestic animals in China
Infection, genetics and evolution, Vol.20, pp.298-303
12/2013
DOI: 10.1016/j.meegid.2013.09.004
PMID: 24060734
Abstract
•In China, about 20% of the animal original influenza A viruses are amantadine resistant.•Mutations associated with amantadine resistance were most common in H1N1, H5N1, and H9N2.•Our results suggest that amantadine continues to be used in these animal populations.•Certain regions of the country are hotspots of resistance in both birds and pigs.
In China, approximately 20% of the animal original influenza A viruses have molecular markers of amantadine resistance. Through phylogenetic data analyses and geospatial statistical analyses, this study suggests emergence of amantadine resistance in animal influenza could be due to selection pressures in China, for example, amantadine usage in some areas.
Details
- Title: Subtitle
- Perspective on emergence and re-emergence of amantadine resistant influenza A viruses in domestic animals in China
- Creators
- Xiu-Feng Wan - Jiangxi Agricultural UniversityMargaret Carrel - University of IowaLi-Ping Long - Mississippi State UniversityAlisa P Alker - University of North Carolina at Chapel HillMike Emch - Department of Geography, University of North Carolina, Chapel Hill, NC 27599, USA
- Resource Type
- Journal article
- Publication Details
- Infection, genetics and evolution, Vol.20, pp.298-303
- DOI
- 10.1016/j.meegid.2013.09.004
- PMID
- 24060734
- NLM abbreviation
- Infect Genet Evol
- ISSN
- 1567-1348
- eISSN
- 1567-7257
- Publisher
- Elsevier B.V
- Grant note
- name: National Science Foundation, award: BCS-0717688
- Language
- English
- Date published
- 12/2013
- Academic Unit
- Epidemiology; Interdisciplinary Programs; Geographical and Sustainability Sciences; Internal Medicine
- Record Identifier
- 9984259388402771
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