Journal article
Phantoms for Noninvasive Blood Glucose Sensing with Near Infrared Transmission Spectroscopy
Photochemistry and photobiology, Vol.67(1), pp.50-55
Received 15 April 1997; accepted 5 September 1997
01/1998
DOI: 10.1111/j.1751-1097.1998.tb05164.x
PMID: 9477765
Abstract
In vivo spectra from human subjects can be simulated with a phantom composed of different layers of water, fat and muscle tissue. All three components are necessary to simulate in vivo spectra collected over the combination spectral region (5000-4000 cm-1). Muscle tissue is not required, however, to accurately simulate overtone spectra (6600-5400 cm-1). The near-IR spectral characteristics of fat and muscle tissue from several animal sources are essentially identical to those found for human tissue, hence, the animal source for these phantom components is not critical. Thickness of each tissue layer can be determined by a regression analysis where the in vivo spectrum of interest is regressed against standard absorbance spectra of the necessary model components (water, fat and muscle). In general, in vivo overtone spectra collected across human webbing tissue with a thickness of 6.7 mm can be simulated with water layer thicknesses ranging from 5.0 to 6.4 mm combined with fat layer thicknesses from 1.4 to 4.2 mm.
Details
- Title: Subtitle
- Phantoms for Noninvasive Blood Glucose Sensing with Near Infrared Transmission Spectroscopy
- Creators
- Jason J Burmeister - Department of Chemistry, University of Iowa, Iowa City, IA, USAHoeil Chung - Department of Chemistry, University of Iowa, Iowa City, IA, USAMark A Arnold - Department of Chemistry, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Photochemistry and photobiology, Vol.67(1), pp.50-55
- Edition
- Received 15 April 1997; accepted 5 September 1997
- Publisher
- Blackwell Publishing Ltd
- DOI
- 10.1111/j.1751-1097.1998.tb05164.x
- PMID
- 9477765
- ISSN
- 0031-8655
- eISSN
- 1751-1097
- Number of pages
- 6
- Language
- English
- Date published
- 01/1998
- Academic Unit
- Center for Biocatalysis and Bioprocessing; Fraternal Order of Eagles Diabetes Research Center; Chemistry
- Record Identifier
- 9984216679902771
Metrics
23 Record Views