Journal article
Pharmaco-endoscopic therapy for weight regain post-gastric bypass: a case report
Journal of surgical case reports, Vol.2023(2), rjad075
02/01/2023
DOI: 10.1093/jscr/rjad075
PMCID: PMC9972808
PMID: 37069846
Abstract
About 1 in every 4 patients who undergo bariatric surgery regains significant amount of weight some time along their journey, posing it as a serious problem that needs to be addressed in a pandemic of obesity. Lifestyle modification, anti-obesity medications, and bariatric endoscopy are multiple therapeutic options that can be used to support any weight loss attempt. A 53-year-old woman with morbid obesity who responded adequately to gastric-bypass regained significant weight 8 years later. We initially approached her post-operative weight regain in a behavioral, pharmacologic non-invasive manner; however, she failed to appropriately respond to several anti-obesity medications. Upper endoscopy revealed a dilated gastric pouch and gastro-jejunal anastomosis (GJA) that was reduced using argon plasma coagulation (APC), but also with a modest response. We then added liraglutide to her APC endo-therapy sessions and subsequentially patient started losing significantly more weight. For selective post-bariatric surgery weight re-gainers, endoscopic and pharmaco-therapy combined may be needed for more effective results.
Details
- Title: Subtitle
- Pharmaco-endoscopic therapy for weight regain post-gastric bypass: a case report
- Creators
- Mohammad Jarrah - University of Iowa Hospitals and ClinicsMohamad Mokadem - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of surgical case reports, Vol.2023(2), rjad075
- Publisher
- Oxford Univ Press
- DOI
- 10.1093/jscr/rjad075
- PMID
- 37069846
- PMCID
- PMC9972808
- ISSN
- 2042-8812
- eISSN
- 2042-8812
- Number of pages
- 4
- Grant note
- name: US Veterans Merit Award, award: #I01 BX004774, #I01 BX005173; DOI: 10.13039/100000738, name: U.S. Department of Veterans Affairs; name: U.S. Government
- Language
- English
- Date published
- 02/01/2023
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984380371102771
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