Journal article
Pharmacotherapy Considerations in Advanced Cardiac Life Support
Pharmacotherapy, Vol.26(12), pp.1703-1729
12/2006
DOI: 10.1592/phco.26.12.1703
PMID: 17125434
Abstract
Cardiac arrest and sudden cardiac death remain major causes of mortality. Early intervention has been facilitated by emergency medical response systems and the development of training programs in basic life support and advanced cardiac life support (ACLS). Despite the implementation of these programs, the likelihood of a meaningful outcome in many life-threatening situations remains poor. Pharmacotherapy plays a role in the management of patients with cardiac arrest, with new guidelines for ACLS available in 2005 providing recommendations for the role of specific drug therapies. Epinephrine continues as a recommended means to facilitate defibrillation in patients with pulseless ventricular tachycardia or ventricular fibrillation; vasopressin is an alternative. Amiodarone is the primary antiarrhythmic drug that has been shown to be effective for facilitation of defibrillation in patients with pulseless ventricular tachycardia or fibrillation and is also used for the management of atrial fibrillation and hemodynamically stable ventricular tachycardia. Epinephrine and atropine are the primary agents used for the management of asystole and pulseless electrical activity. Treatment of electrolyte abnormalities, severe hypotension, pulmonary embolism, acute ischemic stroke, and toxicologic emergencies are important components of ACLS management. Selection of the appropriate drug, dose, and timing and route of administration are among the many challenges faced in this setting. Pharmacists who are properly educated and trained regarding the use of pharmacotherapy for patients requiring ACLS can help maximize the likelihood of positive patient outcomes.
Details
- Title: Subtitle
- Pharmacotherapy Considerations in Advanced Cardiac Life Support
- Creators
- William E. Dager - University of California, DavisCynthia A. Sanoski - University of California, San FranciscoBarbara S. Wiggins - University of VirginiaJames E. Tisdale - Indiana University – Purdue University Indianapolis
- Resource Type
- Journal article
- Publication Details
- Pharmacotherapy, Vol.26(12), pp.1703-1729
- DOI
- 10.1592/phco.26.12.1703
- PMID
- 17125434
- NLM abbreviation
- Pharmacotherapy
- ISSN
- 0277-0008
- eISSN
- 1875-9114
- Publisher
- Blackwell Publishing Ltd
- Number of pages
- 27
- Language
- English
- Date published
- 12/2006
- Academic Unit
- Pharmacy; Pharmacy Practice and Science
- Record Identifier
- 9984721126402771
Metrics
8 Record Views