Journal article
Phenotypic Variation in Mitochondria-Related Performance Traits Across New Zealand Snail Populations
Integrative and comparative biology, Vol.60(2), pp.275-287
08/01/2020
DOI: 10.1093/icb/icaa066
Abstract
Synopsis
Mitochondrial function is critical for energy homeostasis and should shape how genetic variation in metabolism is transmitted through levels of biological organization to generate stability in organismal performance. Mitochondrial function is encoded by genes in two distinct and separately inherited genomes—the mitochondrial genome and the nuclear genome—and selection is expected to maintain functional mito-nuclear interactions. The documented high levels of polymorphism in genes involved in these mito-nuclear interactions and wide variation for mitochondrial function demands an explanation for how and why variability in such a fundamental trait is maintained. Potamopyrgus antipodarum is a New Zealand freshwater snail with coexisting sexual and asexual individuals and, accordingly, contrasting systems of separate vs. co-inheritance of nuclear and mitochondrial genomes. As such, this snail provides a powerful means to dissect the evolutionary and functional consequences of mito-nuclear variation. The lakes inhabited by P. antipodarum span wide environmental gradients, with substantial across-lake genetic structure and mito-nuclear discordance. This situation allows us to use comparisons across reproductive modes and lakes to partition variation in cellular respiration across genetic and environmental axes. Here, we integrated cellular, physiological, and behavioral approaches to quantify variation in mitochondrial function across a diverse set of wild P. antipodarum lineages. We found extensive across-lake variation in organismal oxygen consumption and behavioral response to heat stress and differences across sexes in mitochondrial membrane potential but few global effects of reproductive mode. Taken together, our data set the stage for applying this important model system for sexual reproduction and polyploidy to dissecting the complex relationships between mito-nuclear variation, performance, plasticity, and fitness in natural populations.
Details
- Title: Subtitle
- Phenotypic Variation in Mitochondria-Related Performance Traits Across New Zealand Snail Populations
- Creators
- Emma S Greimann - Department of Biology, University of Iowa, Iowa City, IA, USASamuel F Ward - Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN, USAJames D Woodell - Department of Biology, University of Iowa, Iowa City, IA, USASamantha Hennessey - Department of Biology, University of Iowa, Iowa City, IA, USAMichael R Kline - Department of Biology, University of Iowa, Iowa City, IA, USAJorge A Moreno - Department of Biology, University of Iowa, Iowa City, IA, USAMadeline Peters - Department of Biology, University of Iowa, Iowa City, IA, USAJennifer L Cruise - Department of Biology, University of St. Thomas, Saint Paul, MN, USAKristi L Montooth - School of Biological Sciences, University of Nebraska, Lincoln, NE, USAMaurine Neiman - Department of Biology, University of Iowa, Iowa City, IA, USAJoel Sharbrough - Department of Biology, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Integrative and comparative biology, Vol.60(2), pp.275-287
- DOI
- 10.1093/icb/icaa066
- ISSN
- 1540-7063
- eISSN
- 1557-7023
- Publisher
- Oxford University Press
- Grant note
- DOI: 10.13039/100000001, name: National Science Foundation, award: MCB – 1122176, DEB—1310825, DEB-1753695, DEB—1753851; name: Iowa Academy of Sciences, award: ISF #13-10
- Language
- English
- Date published
- 08/01/2020
- Academic Unit
- Office Of The Provost; Gender, Women's and Sexuality Studies; Biology
- Record Identifier
- 9984217528402771
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