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Phenotypic appearances of prostate utilizing PET-MRI and PET-CT with Ga-68-PSMA, radiolabelled choline and Ga-68-DOTATATE
Journal article   Open access   Peer reviewed

Phenotypic appearances of prostate utilizing PET-MRI and PET-CT with Ga-68-PSMA, radiolabelled choline and Ga-68-DOTATATE

Athar Haroon, Asim Afaq, Soujanya Nuthakki, Alex Freeman, Lorenzo Biassoni, Stefano Fanti, Mohsen Beheshti, Hikmat Jan, Sobhan Vinjamuri, Mark Emberton, …
Nuclear medicine communications, Vol.39(3), pp.196-204
03/01/2018
DOI: 10.1097/MNM.0000000000000797
PMID: 29384832
url
https://discovery.ucl.ac.uk/10050186/1/Emberton_MANUSCRIPT%20UCL%20OPEN%20ACCESS.pdfView
Open Access

Abstract

The objective of this study was to highlight the role of multimodality imaging and present the differential diagnosis of abnormal tracer accumulation in the prostate and periprostatic tissue. Our departments have performed molecular imaging of the prostate utilizing PET-CT and PET-MRI with a range of biomarkers including F-18-FDG, radiolabelled choline, Ga-68-DOTATATE PET-CT and Ga-68-PSMA images. We retrospectively reviewed the varying appearances of the prostate gland in different diseases and incidental findings in periprostatic region. The differential diagnosis of pathologies related to prostate and periprostatic tissue on multimodality imaging includes malakoplakia, rhabdomyosarcoma, lymphoma, prostate cancer, neuroendocrine tumours, uchida changes, rectoprostatic fistula, synchronous malignancies, lymphocoele and schwanoma. There exists a wide differential for abnormal tracer accumulation in the prostate gland. As a radiologist and nuclear medicine physician, it is important to be aware of range of prostatic and periprostatic pathologies.
Life Sciences & Biomedicine Radiology, Nuclear Medicine & Medical Imaging Science & Technology

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