Phosphaturic Mesenchymal Tumor

J C Benson; J A Trejo-Lopez; A M Nassiri; K Eschbacher; M J Link; C L Driscoll; R D Tiegs; J Sfeir; D R DeLone

doi:10.3174/ajnr.A7513

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Phosphaturic Mesenchymal Tumor

J C Benson, J A Trejo-Lopez, A M Nassiri, K Eschbacher, M J Link, C L Driscoll, R D Tiegs, J Sfeir and D R DeLone

American journal of neuroradiology : AJNR, Vol.43(6), pp.817-822

05/19/2022

DOI: 10.3174/ajnr.A7513

PMCID: PMC9172954

PMID: 35589138

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Abstract

Phosphaturic mesenchymal tumors (PMTs) are neoplasms associated with tumor-induced osteomalacia. Patients typically present with pathologic fractures in the setting of chronic hypophosphatemic hyperphosphaturic osteomalacia, as well as gradual muscle weakness, bone pain, and difficulty walking. Because of their rarity and nonspecific symptomatology, phosphaturic mesenchymal tumors often go undiagnosed for years. Even when discovered on imaging, the tumors can be diagnostically challenging for radiologists. Phosphaturic mesenchymal tumors often tend to be small and can be located nearly anywhere in the body, and, therefore, can mimic many other tumors. This case highlights the imaging and pathologic markers of a phosphaturic mesenchymal tumor, often found in a patient with tumor-induced osteomalacia.

Details

Title: Subtitle: Phosphaturic Mesenchymal Tumor
Creators: J C Benson - From the Departments of Radiology (J.C.B., D.R.D.) benson.john3@mayo.edu
J A Trejo-Lopez - National Forum for the Enhancement of Teaching & Learning in Higher Education
A M Nassiri - Otorhinolaryngology (A.M.N., C.L.D.)
K Eschbacher - National Forum for the Enhancement of Teaching & Learning in Higher Education
M J Link - Neurosurgery (M.J.L.)
C L Driscoll - Otorhinolaryngology (A.M.N., C.L.D.)
R D Tiegs - Endocrinology (R.D.T., J.S.), Mayo Clinic, Rochester, Minnesota
J Sfeir - Endocrinology (R.D.T., J.S.), Mayo Clinic, Rochester, Minnesota
D R DeLone - From the Departments of Radiology (J.C.B., D.R.D.)
Resource Type: Journal article
Publication Details: American journal of neuroradiology : AJNR, Vol.43(6), pp.817-822
DOI: 10.3174/ajnr.A7513
PMID: 35589138
PMCID: PMC9172954
NLM abbreviation: AJNR Am J Neuroradiol
ISSN: 0195-6108
eISSN: 1936-959X
Language: English
Date published: 05/19/2022
Academic Unit: Pathology
Record Identifier: 9984276450402771

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