Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?

W K Paj; S E Istrit; M C Deland; C F Wu

doi:10.1126/science.824732

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Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?

Journal article

Peer reviewed

Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?

W K Paj, S E Istrit, M C Deland and C F Wu

Science (American Association for the Advancement of Science), Vol.194(4268), pp.956-959

11/26/1976

DOI: 10.1126/science.824732

PMID: 824732

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Abstract

In norpA mutants of Drosophila melanogaster the phototransduction process is either partially or completely blocked. By using a temperature-sensitive allele, we have found that that norpA mutation has little or no effect on either the rhodopsin-metarhodopsin transition or the machinery of quantum bump production. Thus, the norpA lesion appears to be localized in the intermediate process of phototransduction. Because a temperature-sensitive allele of norpA has been isolated, the norpA gene probably encodes a protein involved in the process.

Temperature

Animals

Biological Transport

Membrane Potentials

Membrane Proteins - physiology

Rhodopsin - physiology

Kinetics

Mutation

Sodium - metabolism

Drosophila melanogaster

Photoreceptor Cells - physiology

Details

Title: Subtitle: Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?
Creators: W K Paj
S E Istrit
M C Deland
C F Wu
Resource Type: Journal article
Publication Details: Science (American Association for the Advancement of Science), Vol.194(4268), pp.956-959
Publisher: United States
DOI: 10.1126/science.824732
PMID: 824732
ISSN: 0036-8075
eISSN: 1095-9203
Language: English
Date published: 11/26/1976
Academic Unit: Iowa Neuroscience Institute; Biology
Record Identifier: 9984070508302771

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