Journal article
Phototriggered Guest Release from a Nonporous Organic Crystal: Remarkable Single-Crystal-to-Single-Crystal Transformation of a Binary Cocrystal Solvate to a Ternary Cocrystal
Journal of the American Chemical Society, Vol.142(49), pp.20772-20777
12/09/2020
DOI: 10.1021/jacs.0c09732
PMID: 33236628
Abstract
The development of organic solids for applications in materials science requires a fundamental understanding of how close packing of molecules can affect structure and function. We report here nonporous organic crystals that release entrapped guest molecules upon application of UV light. We show components of binary cocrystal solvates to undergo an intermolecular photoreaction to generate ternary cocrystals that results in release of entrapped solvent molecules. The phototriggered guest release occurs in a single-crystal-to-single-crystal transformation that is in the absence pores and channels in the solid. The cocrystals are composed of a tetratopic hydrogen-bond-acceptor molecule synthesized in the solid state. The UV-light results in [2 + 2] photodimerization of an isocoumarin to generate a ternary cocrystal with cyclobutane molecules that support guest release.
Details
- Title: Subtitle
- Phototriggered Guest Release from a Nonporous Organic Crystal: Remarkable Single-Crystal-to-Single-Crystal Transformation of a Binary Cocrystal Solvate to a Ternary Cocrystal
- Creators
- Shweta P Yelgaonkar - Department of Chemistry, University of Iowa, Iowa City, Iowa 52245, United StatesGonzalo Campillo-Alvarado - Department of Chemistry, University of Iowa, Iowa City, Iowa 52245, United StatesLeonard R MacGillivray - Department of Chemistry, University of Iowa, Iowa City, Iowa 52245, United States
- Resource Type
- Journal article
- Publication Details
- Journal of the American Chemical Society, Vol.142(49), pp.20772-20777
- DOI
- 10.1021/jacs.0c09732
- PMID
- 33236628
- ISSN
- 0002-7863
- eISSN
- 1520-5126
- Grant note
- DOI: 10.13039/100000078, name: Division of Materials Research, award: DMR-1708673
- Language
- English
- Date published
- 12/09/2020
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Chemistry
- Record Identifier
- 9984216682402771
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