Journal article
Physical Activity Interventions in Preventing Cognitive Decline and Alzheimer-Type Dementia A Systematic Review
Annals of internal medicine, Vol.168(1), pp.30-38
01/02/2018
DOI: 10.7326/M17-1528
PMID: 29255839
Abstract
Background: The prevalence of cognitive impairment and dementia is expected to increase dramatically as the population ages, creating burdens on families and health care systems.
Purpose: To assess the effectiveness of physical activity interventions in slowing cognitive decline and delaying the onset of cognitive impairment and dementia in adults without diagnosed cognitive impairments.
Data Sources: Several electronic databases from January 2009 to July 2017 and bibliographies of systematic reviews.
Study Selection: Trials published in English that lasted 6 months or longer, enrolled adults without clinically diagnosed cognitive impairments, and compared cognitive and dementia outcomes between physical activity interventions and inactive controls.
Data Extraction: Extraction by 1 reviewer and confirmed by a second; dual-reviewer assessment of risk of bias; consensus determination of strength of evidence.
Data Synthesis: Of 32 eligible trials, 16 with low to moderate risk of bias compared a physical activity intervention with an inactive control. Most trials had 6-month follow-up; a few had 1-or 2-year follow-up. Evidence was insufficient to draw conclusions about the effectiveness of aerobic training, resistance training, or tai chi for improving cognition. Low-strength evidence showed that multicomponent physical activity interventions had no effect on cognitive function. Low-strength evidence showed that a multidomain intervention comprising physical activity, diet, and cognitive training improved several cognitive outcomes. Evidence regarding effects on dementia prevention was insufficient for all physical activity interventions.
Limitation: Heterogeneous interventions and cognitive test measures, small and underpowered studies, and inability to assess the clinical significance of cognitive test outcomes.
Conclusion: Evidence that short-term, single-component physical activity interventions promote cognitive function and prevent cognitive decline or dementia in older adults is largely insufficient. A multidomain intervention showed a delay in cognitive decline (low-strength evidence).
Details
- Title: Subtitle
- Physical Activity Interventions in Preventing Cognitive Decline and Alzheimer-Type Dementia A Systematic Review
- Creators
- Michelle Brasure - University of MinnesotaPriyanka Desai - University of MinnesotaHeather Davila - University of MinnesotaVictoria A. Nelson - University of MinnesotaCollin Calvert - University of MinnesotaEric Jutkowitz - Brown UniversityMary Butler - University of MinnesotaHoward A. Fink - University of MinnesotaEdward Ratner - Minneapolis VA Health Care SystemLaura S. Hemmy - University of MinnesotaJ. Riley McCarten - University of MinnesotaTerry R. Barclay - University of MinnesotaRobert L. Kane - University of Minnesota
- Resource Type
- Journal article
- Publication Details
- Annals of internal medicine, Vol.168(1), pp.30-38
- Publisher
- Amer Coll Physicians
- DOI
- 10.7326/M17-1528
- PMID
- 29255839
- ISSN
- 0003-4819
- eISSN
- 1539-3704
- Number of pages
- 10
- Grant note
- 290-2015-00008-I / Agency for Healthcare Research and Quality; United States Department of Health & Human Services; Agency for Healthcare Research & Quality
- Language
- English
- Date published
- 01/02/2018
- Academic Unit
- Occupational and Environmental Health; Internal Medicine
- Record Identifier
- 9984359782102771
Metrics
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