Journal article
Physicochemical and rheological characterization of different Carnoy's solutions applied in oral and maxillofacial surgery
Journal of Raman spectroscopy, Vol.48(10), pp.1375-1384
10/2017
DOI: 10.1002/jrs.5227
Abstract
Carnoy's solution has been widely undertaken as adjunctive therapy for benign odontogenic tumors. Although its outcomes were highly investigated, little information is available regarding its mechanism of action and the role of chloroform in composition. The aim of this study was to characterize Carnoy's solution (with and without chloroform) in order to survey its physicochemical and pharmacological properties. UV/Vis spectroscopy, Raman microspectroscopy, viscosity assessment, pH analysis, and ion (Fe3+) concentration were studied. All solutions were prepared by the same operator and assayed at each 7 days within a 4-week period. All solutions depicted acidic pH whereas the viscosity was increased by the addition of chloroform. Starting in the seventh day after preparation, solutions with chloroform showed iron precipitation when nonfiltered. Carnoy's solution without chloroform was stable during the survey period as evidenced by Raman spectroscopy. In conclusion, Carnoy's solution possesses an acidic characteristic, it is stable when stored at room temperature, and precipitates iron salts when in the presence of chloroform in a nonfiltered solution. The chloroform increases the viscosity of the solution and makes its pH slightly more acidic when compared to the Carnoy's solution without chloroform. Raman spectroscopy favored the evaluation of components' stability in solutions by using the spectra analysis and the established correlations between the peaks in different periods.
Details
- Title: Subtitle
- Physicochemical and rheological characterization of different Carnoy's solutions applied in oral and maxillofacial surgery
- Creators
- Francisco Samuel Rodrigues Carvalho - Univ Fed Ceara, Div Oral & Maxillofacial Surg, Rua Monsenhor Furtado, BR-60430350 Fortaleza, Ceara, BrazilVictor Pinheiro Feitosa - Paulo Picanco Sch Dent, Fortaleza, Ceara, BrazilSaid Goncalves da Cruz Fonseca - Universidade Federal do CearáThiago Dias de Vasconcelos Araujo - Universidade Federal do CearáEduardo Costa Studart Soares - Univ Fed Ceara, Walter Cantidio Univ Hosp, Div Oral & Maxillofacial Surg, Fortaleza, Ceara, BrazilCristiane Sa Roriz Fonteles - Univ Fed Ceara, Sch Dent, Fortaleza, Ceara, BrazilThyciana Rodrigues Ribeiro - Universidade Federal do CearáFabio Wildson Gurgel Costa - Univ Fed Ceara, Walter Cantidio Univ Hosp, Div Oral Radiol, Fortaleza, Ceara, Brazil
- Resource Type
- Journal article
- Publication Details
- Journal of Raman spectroscopy, Vol.48(10), pp.1375-1384
- Publisher
- Wiley
- DOI
- 10.1002/jrs.5227
- ISSN
- 0377-0486
- eISSN
- 1097-4555
- Number of pages
- 10
- Language
- English
- Date published
- 10/2017
- Academic Unit
- Operative Dentistry
- Record Identifier
- 9984654472302771
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