Journal article
Platelet-Endothelium Interactions
The New England journal of medicine, Vol.328(9), pp.628-635
03/04/1993
DOI: 10.1056/NEJM199303043280907
PMID: 8429855
Abstract
The recognition that the restoration of patency to occluded blood vessels can improve clinical outcomes has led to intense interest in the formation and dissolution of platelet thrombi and in the pathobiologic features of vascular repair after an injury. To study these events in an experimental model, many investigators challenge isolated platelets or endothelium with stimuli that represent physiologic or pathologic mediators, such as thrombin or adenosine diphosphate (ADP), and find that these agonists cause the generation of intracellular mediators that can markedly alter the function of each cell type. A critical facet of thrombus formation and vascular response to . . .
Details
- Title: Subtitle
- Platelet-Endothelium Interactions
- Creators
- J. Anthony WareDonald D Heistad
- Resource Type
- Journal article
- Publication Details
- The New England journal of medicine, Vol.328(9), pp.628-635
- Publisher
- Massachusetts Medical Society
- DOI
- 10.1056/NEJM199303043280907
- PMID
- 8429855
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Language
- English
- Date published
- 03/04/1993
- Academic Unit
- Cardiovascular Medicine; Neuroscience and Pharmacology; Internal Medicine
- Record Identifier
- 9984040373102771
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