Journal article
Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome
Clinical kidney journal, Vol.9(4), pp.572-575
05/04/2016
DOI: 10.1093/ckj/sfw025
PMCID: PMC4957713
PMID: 27478599
Abstract
Pneumococcal-associated hemolytic uremic syndrome (pHUS) is a rare but severe complication of invasive
Streptococcus pneumoniae
infection. We report the case of a 12-year-old female with steroid-resistant nephrotic syndrome treated with adrenocorticotrophic hormone
(
H.P. Acthar
®
Gel), who developed pneumococcal pneumonia and subsequent pHUS. While nephrotic syndrome is a well-known risk factor for invasive pneumococcal disease, this is the first reported case of pHUS in an adolescent patient with nephrotic syndrome, and reveals novel challenges in the diagnosis, treatment and potential prevention of this complication.
Details
- Title: Subtitle
- Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome
- Creators
- Andrew P. Groves - Washington University in St. LouisPatrick Reich - Washington University in St. LouisBinayak Sigdel - Washington University in St. LouisT. Keefe Davis - Washington University in St. Louis
- Resource Type
- Journal article
- Publication Details
- Clinical kidney journal, Vol.9(4), pp.572-575
- DOI
- 10.1093/ckj/sfw025
- PMID
- 27478599
- PMCID
- PMC4957713
- NLM abbreviation
- Clin Kidney J
- ISSN
- 2048-8505
- eISSN
- 2048-8513
- Publisher
- Oxford University Press
- Language
- English
- Date published
- 05/04/2016
- Academic Unit
- Stead Family Department of Pediatrics; Hematology/Oncology
- Record Identifier
- 9984353937602771
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