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Poised polymerases: on your mark...get set...go
Journal article   Open access   Peer reviewed

Poised polymerases: on your mark...get set...go

David H Price
Molecular cell, Vol.30(1), pp.7-10
04/11/2008
DOI: 10.1016/j.molcel.2008.03.001
PMID: 18406322
url
https://doi.org/10.1016/j.molcel.2008.03.001View
Published (Version of record) Open Access

Abstract

Recent global analyses have determined that many Drosophila and human genes have engaged polymerase molecules trapped immediately downstream of promoters. These results strongly implicate RNA polymerase II elongation control as a major regulator of differentiation and development.
Promoter Regions, Genetic Protein Biosynthesis Animals Humans Gene Expression Regulation RNA Polymerase II - genetics Transcription, Genetic Positive Transcriptional Elongation Factor B - metabolism RNA Polymerase II - metabolism

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