Polymers for Osmotic Self-Inflating Expanders in Oral Surgical Procedures: A Comprehensive Review

Alejandro Elizalde Hernandez; Natalia Link Bahr; Matheus Coelho Blois; Carlos Enrique Cuevas-Suarez; Evandro Piva; Mateus Bertolini Fernandes dos Santos; Carla Lucia David Pena; Rafael Guerra Lund

doi:10.3390/polym17040441

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Polymers for Osmotic Self-Inflating Expanders in Oral Surgical Procedures: A Comprehensive Review

Journal article

Open access

Peer reviewed

Polymers for Osmotic Self-Inflating Expanders in Oral Surgical Procedures: A Comprehensive Review

Alejandro Elizalde Hernandez, Natalia Link Bahr, Matheus Coelho Blois, Carlos Enrique Cuevas-Suarez, Evandro Piva, Mateus Bertolini Fernandes dos Santos, Carla Lucia David Pena and Rafael Guerra Lund

Polymers, Vol.17(4), 441

02/08/2025

DOI: 10.3390/polym17040441

PMCID: PMC11859471

PMID: 40006103

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https://doi.org/10.3390/polym17040441View

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Abstract

Soft-tissue expansion is a critical challenge in regenerative oral surgeries. This scoping review maps the research on polymers used in osmotic self-inflating expanders, assessing their applications, characteristics, and potential in oral surgical procedures. The study analyzed 19 articles from the PubMed, Scopus, Web of Science, and Embase databases, primarily focusing on in vivo research (78.9%) investigating polymeric tissue expanders. The review examined polymer compositions, methodologies, and tissue responses across various animal models. Osmed (R) hydrogel was the most studied material, with research exploring its expansion capabilities in rabbits, goats, pigs, rats, and beagle dogs. The findings showed diverse tissue expansion ranges and minimal inflammatory responses, indicating the potential for oral surgical applications. Despite promising results, gaps such as inconsistent expansion measurements and the lack of standardized protocols were identified. These findings highlight the need for further research to develop new polymer formulations and optimize device design to enhance safety, efficacy, and clinical predictability. This review provides a foundation for advancing polymeric tissue expander technologies, offering the potential for safer and more effective minimally invasive regenerative oral surgeries.

Physical Sciences

Polymer Science

Science & Technology

Details

Title: Subtitle: Polymers for Osmotic Self-Inflating Expanders in Oral Surgical Procedures: A Comprehensive Review
Creators: Alejandro Elizalde Hernandez - Univ Fed Pelotas, Pelotas Dent Sch, Grad Program Dent, BR-96015560 Pelotas, Brazil
Natalia Link Bahr - Universidade Federal de Pelotas
Matheus Coelho Blois - Universidade Federal de Pelotas
Carlos Enrique Cuevas-Suarez - Universidade Federal de Pelotas
Evandro Piva - Universidade Federal de Pelotas
Mateus Bertolini Fernandes dos Santos - Universidade Federal de Pelotas
Carla Lucia David Pena - Univ Fed Pelotas, Pelotas Dent Sch, Grad Program Dent, BR-96015560 Pelotas, Brazil
Rafael Guerra Lund - Universidade Federal de Pelotas
Resource Type: Journal article
Publication Details: Polymers, Vol.17(4), 441
DOI: 10.3390/polym17040441
PMID: 40006103
PMCID: PMC11859471
NLM abbreviation: Polymers (Basel)
ISSN: 2073-4360
eISSN: 2073-4360
Publisher: Mdpi
Number of pages: 12
Grant note: 001 / Coordination for the Improvement of Higher Education Personnel (CAPES); Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) FAPERGS; Fundacao de Amparo a Ciencia e Tecnologia do Estado do Rio Grande do Sul (FAPERGS) 24/2551-0001449-7 / National Council for Scientific and Technological Development (CNPq); Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) DT-1D; 306225/2021-2; 315938/2023-4 / Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil-Finance; Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
Language: English
Date published: 02/08/2025
Academic Unit: Prosthodontics
Record Identifier: 9984945910702771

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