Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3→p35

Thomas B Shows; Roger L Eddy; Mary G Byers; Yoshimitsu Fukushima; Catherine R DeHaven; Jeffrey C Murray; Graeme I Bell

doi:10.2337/diab.36.4.546

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Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3→p35

Journal article

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Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3→p35

Thomas B Shows, Roger L Eddy, Mary G Byers, Yoshimitsu Fukushima, Catherine R DeHaven, Jeffrey C Murray and Graeme I Bell

Diabetes (New York, N.Y.), Vol.36(4), pp.546-549

1987

DOI: 10.2337/diab.36.4.546

PMID: 3028891

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Abstract

The glucose transporter is a membrane glycoprotein that is involved in the uptake of glucose by most, if not all, animal cells. A cloned cDNA that encodes the human protein was used to map the gene to a specific chromosomal region and to identify a DNA polymorphism. The human gene (designated GLUT) was assigned to chromosome 1p31.3----p35 by hybridization of the probe to DNA from a panel of human-mouse somatic cell hybrids containing different human chromosomes and by in situ hybridization to isolated metaphase chromosomes. The most likely location of GLUT is in 1p33. A common two-allele restriction-fragment-length polymorphism was identified with Xba I.

Fundamental and applied biological sciences. Psychology

Classical genetics, quantitative genetics, hybrids

Human

Biological and medical sciences

Genetics of eukaryotes. Biological and molecular evolution

Details

Title: Subtitle: Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3→p35
Creators: Thomas B Shows - New York state dep. health, Roswell Park memorial inst., Buffalo NY 14263, United States
Roger L Eddy - New York state dep. health, Roswell Park memorial inst., Buffalo NY 14263, United States
Mary G Byers - New York state dep. health, Roswell Park memorial inst., Buffalo NY 14263, United States
Yoshimitsu Fukushima - New York state dep. health, Roswell Park memorial inst., Buffalo NY 14263, United States
Catherine R DeHaven - University of Iowa
Jeffrey C Murray - University of Iowa
Graeme I Bell - University of Iowa
Resource Type: Journal article
Publication Details: Diabetes (New York, N.Y.), Vol.36(4), pp.546-549
DOI: 10.2337/diab.36.4.546
PMID: 3028891
NLM abbreviation: Diabetes
ISSN: 0012-1797
eISSN: 1939-327X
Publisher: American Diabetes Association; Alexandria, VA
Language: English
Date published: 1987
Academic Unit: Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
Record Identifier: 9984025691102771

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