Journal article
Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps
Genetics (Austin), Vol.179(3), pp.1601-1655
07/2008
DOI: 10.1534/genetics.107.086074
PMCID: PMC2475758
PMID: 18622037
Abstract
The sequencing of the 12 genomes of members of the genus Drosophila was taken as an opportunity to reevaluate the genetic and physical maps for 11 of the species, in part to aid in the mapping of assembled scaffolds. Here, we present an overview of the importance of cytogenetic maps to Drosophila biology and to the concepts of chromosomal evolution. Physical and genetic markers were used to anchor the genome assembly scaffolds to the polytene chromosomal maps for each species. In addition, a computational approach was used to anchor smaller scaffolds on the basis of the analysis of syntenic blocks. We present the chromosomal map data from each of the 11 sequenced non-Drosophila melanogaster species as a series of sections. Each section reviews the history of the polytene chromosome maps for each species, presents the new polytene chromosome maps, and anchors the genomic scaffolds to the cytological maps using genetic and physical markers. The mapping data agree with Muller's idea that the majority of Drosophila genes are syntenic. Despite the conservation of genes within homologous chromosome arms across species, the karyotypes of these species have changed through the fusion of chromosomal arms followed by subsequent rearrangement events.
Details
- Title: Subtitle
- Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps
- Creators
- Stephen W Schaeffer - Department of Biology and Institute of Molecular Evolutionary Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA. sws4@psu.eduArjun BhutkarBryant F McAllisterMuneo MatsudaLuciano M MatzkinPatrick M O'GradyClaudia RohdeVera L S ValenteMontserrat AguadéWyatt W AndersonKevin EdwardsAna C L GarciaJosh GoodmanJames HartiganEiko KataokaRichard T LapointElena R LozovskyCarlos A MachadoMohamed A F NoorMontserrat PapaceitLaura K ReedStephen RichardsTania T RiegerSusan M RussoHajime SatoCarmen SegarraDouglas R SmithVictor StreletsYoshiko N TobariYoshihiko TomimuraMarvin WassermanThomas WattsRobert WilsonKiyohito YoshidaTherese A MarkowWilliam M GelbartThomas C KaufmanTemple F Smith - Boston University
- Resource Type
- Journal article
- Publication Details
- Genetics (Austin), Vol.179(3), pp.1601-1655
- Publisher
- United States
- DOI
- 10.1534/genetics.107.086074
- PMID
- 18622037
- PMCID
- PMC2475758
- ISSN
- 0016-6731
- eISSN
- 1943-2631
- Grant note
- R01 GM076051-01A2 / NIGMS NIH HHS HG000739 / NHGRI NIH HHS P41 HG000739 / NHGRI NIH HHS U41 HG000739 / NHGRI NIH HHS R01 GM076051 / NIGMS NIH HHS
- Language
- English
- Date published
- 07/2008
- Academic Unit
- Biology
- Record Identifier
- 9983991960202771
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