Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects

Erin B Stallings; Jennifer L Isenburg; Tyiesha D Short; Dominique Heinke; Russell S Kirby; Paul A Romitti; Mark A Canfield; Leslie A O'Leary; Rebecca F Liberman; Nina E Forestieri; Wendy N Nembhard; Theresa Sandidge; Eirini Nestoridi; Jason L Salemi; Amy E Nance; Kirstan Duckett; Glenda M Ramirez; Xiaoyi Shan; Jing Shi; Philip J Lupo

doi:10.1002/bdr2.1607

Back

Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects

Journal article

Open access

Peer reviewed

Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects

Erin B Stallings, Jennifer L Isenburg, Tyiesha D Short, Dominique Heinke, Russell S Kirby, Paul A Romitti, Mark A Canfield, Leslie A O'Leary, Rebecca F Liberman, Nina E Forestieri, …

Birth defects research, Vol.111(18), pp.1436-1447

11/01/2019

DOI: 10.1002/bdr2.1607

PMCID: PMC6886260

PMID: 31642616

Files and links (1)

url

https://doi.org/10.1002/bdr2.1607View

Published (Version of record) Open Access

Abstract

In this report, the National Birth Defects Prevention Network (NBDPN) examines and compares gastroschisis and omphalocele for a recent 5-year birth cohort using data from 30 population-based birth defect surveillance programs in the United States. As a special call for data for the 2019 NBDPN Annual Report, state programs reported expanded data on gastroschisis and omphalocele for birth years 2012-2016. We estimated the overall prevalence (per 10,000 live births) and 95% confidence intervals (CI) for each defect as well as by maternal race/ethnicity, maternal age, infant sex, and case ascertainment methodology utilized by the program (active vs. passive). We also compared distribution of cases by maternal and infant factors and presence/absence of other birth defects. The overall prevalence estimates (per 10,000 live births) were 4.3 (95% CI: 4.1-4.4) for gastroschisis and 2.1 (95% CI: 2.0-2.2) for omphalocele. Gastroschisis was more frequent among young mothers (<25 years) and omphalocele more common among older mothers (>40 years). Mothers of infants with gastroschisis were more likely to be underweight/normal weight prior to pregnancy and mothers of infants with omphalocele more likely to be overweight/obese. Omphalocele was twice as likely as gastroschisis to co-occur with other birth defects. This report highlights important differences between gastroschisis and omphalocele. These differences indicate the importance of distinguishing between these defects in epidemiologic assessments. The report also provides additional data on co-occurrence of gastroschisis and omphalocele with other birth defects. This information can provide a basis for future research to better understand these defects.

Abdominal Wall - physiopathology

Abnormalities, Multiple - epidemiology

Adult

Congenital Abnormalities - epidemiology

Congenital Abnormalities - ethnology

Continental Population Groups

Digestive System Abnormalities - epidemiology

Digestive System Abnormalities - ethnology

Female

Gastroschisis - epidemiology

Hernia, Umbilical - epidemiology

Humans

Infant

Infant, Newborn

Live Birth

Male

Maternal Age

Middle Aged

Mothers

Population Surveillance - methods

Pregnancy

Prevalence

Registries

Risk Factors

United States - epidemiology

United States - ethnology

Details

Title: Subtitle: Population-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects
Creators: Erin B Stallings - Carter Consulting, Incorporated, Atlanta, Georgia
Jennifer L Isenburg - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia
Tyiesha D Short - Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee
Dominique Heinke - Massachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts
Russell S Kirby - College of Public Health, University of South Florida, Tampa, Florida
Paul A Romitti - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa
Mark A Canfield - Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, Texas
Leslie A O'Leary - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia
Rebecca F Liberman - Massachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts
Nina E Forestieri - Division of Public Health, North Carolina Department of Health and Human Services, Raleigh, North Carolina
Wendy N Nembhard - Department of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Arkansas Center for Birth Defects Research and Prevention, Little Rock, Arkansas
Theresa Sandidge - Illinois Department of Public Health, Springfield, Illinois
Eirini Nestoridi - Massachusetts Department of Public Health, Center for Birth Defects Research and Prevention, Boston, Massachusetts
Jason L Salemi - Department of Family and Community Medicine, Baylor College of Medicine, Houston, Texas
Amy E Nance - Utah Birth Defect Network, Division of Family Health and Preparedness, Utah Department of Health, Salt Lake City, Utah
Kirstan Duckett - Ohio Department of Health, Columbus, Ohio
Glenda M Ramirez - Arizona Birth Defects Monitoring Program, Arizona Department of Health Services, Phoenix, Arizona
Xiaoyi Shan - Arkansas Reproductive Health Monitoring System, Arkansas Children's Research Institute, Little Rock, Arkansas
Jing Shi - Special Child Health and Early Intervention Services, New Jersey Department of Health, Trenton, New Jersey
Philip J Lupo - Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas
Resource Type: Journal article
Publication Details: Birth defects research, Vol.111(18), pp.1436-1447
DOI: 10.1002/bdr2.1607
PMID: 31642616
PMCID: PMC6886260
NLM abbreviation: Birth Defects Res
ISSN: 2472-1727
eISSN: 2472-1727
Publisher: Wiley
Grant note: CC999999 / Intramural CDC HHS U01 DD001035 / NCBDD CDC HHS U01 DD001223 / NCBDD CDC HHS
Language: English
Date published: 11/01/2019
Academic Unit: Epidemiology; Biostatistics
Record Identifier: 9984213370102771

Metrics

30 Record Views

65 Times Cited - Web of Science