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Porous Polymer and Cell Composites That Self‐Assemble In Situ
Journal article   Peer reviewed

Porous Polymer and Cell Composites That Self‐Assemble In Situ

A.K Salem, F.R.A.J Rose, R.O.C Oreffo, X Yang, M.C Davies, J.R Mitchell, C J Roberts, S Stolnik‐Trenkic, S.J.B Tendler, P.M Williams, …
Advanced Materials, Vol.15(3), pp.210-213
02/2003
DOI: 10.1002/adma.200390047

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Abstract

A cell‐laden 3D network is formed upon the addition of avidin to biotinylated polymer particles in the presence of a suspension of cells (see Figure). Applications in tissue engineering and drug delivery are demonstrated; a shape‐retaining biomaterial is formed within minutes of injecting the components into a cavity. The molecular interaction mechanism of self‐assembly differentiates this polymer/cell composite from other injectable systems.
Tissue Engineering Biotin Polymer particles Cells Polymer scaffolds, porous Self‐assembly

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