Journal article
Positron emission tomographic measurement of bone marrow blood flow to the pelvis and lumbar vertebrae in young normal adults [published erratum appears in Blood 1994 Nov 15;84(10):3602]
Blood, Vol.83(4), pp.958-963
02/15/1994
DOI: 10.1182/blood.V83.4.958.958
PMID: 8111065
Abstract
Abstract Ten young normal adults had pelvic and lumbar vertebral body bone marrow blood flow examined using [15O]water and positron emission tomography (PET) in a study designed to assess the feasibility and reproducibility of the PET technique for measuring marrow blood flow to various marrow regions. The procedure was well tolerated. Repeated blood flow measurements obtained from two consecutive [15O]water exams on each individual subject were highly reproducible. In addition, there was minimal variation in marrow blood flow from individual to individual and no gender differences were noted. In contrast, mean+/-SD bone marrow blood flows (expressed as milliliters per minute per 100 g) at selected anatomical sites were significantly different and were as follows: lower lumbar vertebral bodies, 17.6+/-3.1; most posterior and superior pelvis (conventional site of percutaneous bone marrow biopsy), 14.3+/-3.1; and total superior pelvis, 11.1+/-2.0. We conclude that PET is a relatively noninvasive, simple, and reproducible technique for measuring bone marrow blood flow. Marrow blood flow is consistent between normal young subjects, but varies significantly between different anatomic regions of the marrow.
Details
- Title: Subtitle
- Positron emission tomographic measurement of bone marrow blood flow to the pelvis and lumbar vertebrae in young normal adults [published erratum appears in Blood 1994 Nov 15;84(10):3602]
- Creators
- D Kahn - Department of Radiology, University of Iowa College of Medicine, Iowa CityG J Weiner - Department of Radiology, University of Iowa College of Medicine, Iowa CityS Ben-Haim - Department of Radiology, University of Iowa College of Medicine, Iowa CityL L Ponto - Department of Radiology, University of Iowa College of Medicine, Iowa CityM T Madsen - Department of Radiology, University of Iowa College of Medicine, Iowa CityD L Bushnell - Department of Radiology, University of Iowa College of Medicine, Iowa CityG L Watkins - Department of Radiology, University of Iowa College of Medicine, Iowa CityE A Argenyi - Department of Radiology, University of Iowa College of Medicine, Iowa CityR D Hichwa - Department of Radiology, University of Iowa College of Medicine, Iowa City
- Resource Type
- Journal article
- Publication Details
- Blood, Vol.83(4), pp.958-963
- DOI
- 10.1182/blood.V83.4.958.958
- PMID
- 8111065
- NLM abbreviation
- Blood
- ISSN
- 0006-4971
- eISSN
- 1528-0020
- Language
- English
- Date published
- 02/15/1994
- Academic Unit
- Radiology; Research Administration; Hematology, Oncology, and Blood & Marrow Transplantation; Pharmaceutical Sciences and Experimental Therapeutics; Physics and Astronomy; Radiation Oncology; Internal Medicine
- Record Identifier
- 9984051542502771
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