Journal article
Possible mechanisms responsible for the reduced intestinal flora in hibernating leopard frogs (Rana pipiens)
Applied and environmental microbiology, Vol.54(9), pp.2311-2317
09/1988
DOI: 10.1128/AEM.54.9.2311-2317.1988
PMCID: PMC202855
PMID: 3263839
Abstract
Mechanisms and factors that normally control the large intestinal flora were investigated to determine whether changes in these parameters could account for the decreased bacterial concentration and facultative nature of the flora found in hibernating frogs. It appeared that low temperatures and limited nutrients were the main factors responsible for the decrease in the bacterial concentration and may also have been responsible for the increase in the proportions of facultative organisms, since no change in the redox potential was seen. The hibernating frogs were extremely sluggish in the removal of India ink particles from the circulatory system by the Kupffer cells of the liver compared with nonhibernating frogs. They were unable to mount an antibody response to bovine serum albumin, but their serum did exhibit killing of Pseudomonas paucimobilis, suggesting opsonization by preformed antibody and complement. The role of these host factors in protecting the hibernating frog against this indigenous flora is discussed.
Details
- Title: Subtitle
- Possible mechanisms responsible for the reduced intestinal flora in hibernating leopard frogs (Rana pipiens)
- Creators
- J A Banas - Dental Research Institute, University of Michigan, Ann Arbor 48109W J Loesche - Dental Research Institute, University of Michigan, Ann Arbor 48109G W Nace - Dental Research Institute, University of Michigan, Ann Arbor 48109
- Resource Type
- Journal article
- Publication Details
- Applied and environmental microbiology, Vol.54(9), pp.2311-2317
- DOI
- 10.1128/AEM.54.9.2311-2317.1988
- PMID
- 3263839
- PMCID
- PMC202855
- ISSN
- 0099-2240
- eISSN
- 1098-5336
- Language
- English
- Date published
- 09/1988
- Academic Unit
- Pediatric Dentistry; Dental Research
- Record Identifier
- 9984065989802771
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