Post-COVID-19 Fatigue: Potential Contributing Factors

Thorsten Rudroff; Alexandra C. Fietsam; Justin R. Deters; Andrew D. Bryant; John Kamholz

doi:10.3390/brainsci10121012

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Post-COVID-19 Fatigue: Potential Contributing Factors

Journal article

Open access

Peer reviewed

Post-COVID-19 Fatigue: Potential Contributing Factors

Thorsten Rudroff, Alexandra C. Fietsam, Justin R. Deters, Andrew D. Bryant and John Kamholz

Brain sciences, Vol.10(12), pp.1-7

12/01/2020

DOI: 10.3390/brainsci10121012

PMCID: PMC7766297

PMID: 33352638

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Abstract

Much of the spotlight for coronavirus disease 2019 (COVID-19) is on the acute symptoms and recovery. However, many recovered patients face persistent physical, cognitive, and psychological symptoms well past the acute phase. Of these symptoms, fatigue is one of the most persistent and debilitating. In this "perspective article," we define fatigue as the decrease in physical and/or mental performance that results from changes in central, psychological, and/or peripheral factors due to the COVID-19 disease and propose a model to explain potential factors contributing to post-COVID-19 fatigue. According to our model, fatigue is dependent on conditional and physiological factors. Conditional dependency comprises the task, environment, and physical and mental capacity of individuals, while physiological factors include central, psychological, and peripheral aspects. This model provides a framework for clinicians and researchers. However, future research is needed to validate our proposed model and elucidate all mechanisms of fatigue due to COVID-19.

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Details

Title: Subtitle: Post-COVID-19 Fatigue: Potential Contributing Factors
Creators: Thorsten Rudroff - University of Iowa
Alexandra C. Fietsam - University of Iowa
Justin R. Deters - University of Iowa
Andrew D. Bryant - University of Iowa Hospitals and Clinics
John Kamholz - University of Iowa Hospitals and Clinics
Resource Type: Journal article
Publication Details: Brain sciences, Vol.10(12), pp.1-7
DOI: 10.3390/brainsci10121012
PMID: 33352638
PMCID: PMC7766297
NLM abbreviation: Brain Sci
ISSN: 2076-3425
eISSN: 2076-3425
Publisher: Mdpi
Number of pages: 7
Language: English
Date published: 12/01/2020
Academic Unit: Neurology; Psychiatry; General Internal Medicine; Health, Sport, and Human Physiology ; Internal Medicine
Record Identifier: 9984259642402771

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