Journal article
Post-infectious bronchiolitis obliterans: Can CT scan findings at early age anticipate lung function?
Pediatric pulmonology, Vol.45(4), pp.315-319
04/2010
DOI: 10.1002/ppul.21115
PMID: 20205267
Abstract
Background
The image findings of post-infectious bronchiolitis obliterans (PIBO) have been described, however, we do not know if such findings can predict lung function (LF) deterioration with increasing patient age. Aim: To assess whether computed tomography (CT) abnormalities detected at an early stage of the disease can anticipate abnormal LF a decade later in children with PIBO.
Methods
We compared CT scans of 21 children with PIBO, done within their first 3 years of life, and their actual LF. To evaluate CT scans we used a modified Bhalla score and, for LF, FEV1 as percentage of predicted values. We calculated prevalence ratios (PRs) by comparing the proportion of patients with worst CT score and worst LF, with the proportion of those with best CT score and worst LF.
Results
PR was 1.17 (CI 1.02; 1.34, P = 0.02).
Conclusions
The CT finding early in the life of children with PIBO, when assessed by the Bhalla, score seem to anticipate future LF status.
Details
- Title: Subtitle
- Post-infectious bronchiolitis obliterans: Can CT scan findings at early age anticipate lung function?
- Creators
- Rita Mattiello - Universidade Federal do Rio Grande do SulEdgar E. Sarria - Universidad de Santiago de ChileJavier Mallol - Universidad de Santiago de ChileGilberto B. Fischer - Universidade Federal de Ciências da Saúde de Porto AlegreHelena Mocelin - Hospital Nossa Senhora da ConceiçãoRodrigo Bello - Hospital Nossa Senhora da ConceiçãoJose A.M. Flores - Hospital Nossa Senhora da ConceiçãoKlaus Irion - University of LiverpoolYvonne Jones - University of Liverpool
- Resource Type
- Journal article
- Publication Details
- Pediatric pulmonology, Vol.45(4), pp.315-319
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/ppul.21115
- PMID
- 20205267
- ISSN
- 8755-6863
- eISSN
- 1099-0496
- Number of pages
- 5
- Language
- English
- Date published
- 04/2010
- Academic Unit
- Radiology
- Record Identifier
- 9984697628702771
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