Postfatigue potentiation of the paralyzed soleus muscle : evidence for adaptation with long-term electrical stimulation training

Richard K SHIELDS; Shauna DUDLEY-JAVOROSKI; Andrew E LITTMANN

doi:10.1152/japplphysiol.00099.2006

Back

Postfatigue potentiation of the paralyzed soleus muscle : evidence for adaptation with long-term electrical stimulation training

Journal article

Peer reviewed

Postfatigue potentiation of the paralyzed soleus muscle : evidence for adaptation with long-term electrical stimulation training

Richard K SHIELDS, Shauna DUDLEY-JAVOROSKI and Andrew E LITTMANN

Journal of applied physiology (1985), Vol.101(2), pp.556-565

2006

DOI: 10.1152/japplphysiol.00099.2006

PMCID: PMC3270308

PMID: 16575026

View Online

Abstract

Understanding the torque output behavior of paralyzed muscle has important implications for the use of functional neuromuscular electrical stimulation systems. Postfatigue potentiation is an augmentation of peak muscle torque during repetitive activation after a fatigue protocol. The purposes of this study were 1) to quantify postfatigue potentiation in the acutely and chronically paralyzed soleus and 2) to determine the effect of long-term soleus electrical stimulation training on the potentiation characteristics of recently paralyzed soleus muscle. Five subjects with chronic paralysis (>2 yr) demonstrated significant postfatigue potentiation during a repetitive soleus activation protocol that induced low-frequency fatigue. Ten subjects with acute paralysis (<6 mo) demonstrated no torque potentiation in response to repetitive stimulation. Seven of these acute subjects completed 2 yr of home-based isometric soleus electrical stimulation training of one limb (compliance = 83%; 8,300 contractions/wk). With the early implementation of electrically stimulated training, potentiation characteristics of trained soleus muscles were preserved as in the acute postinjury state. In contrast, untrained limbs showed marked postfatigue potentiation at 2 yr after spinal cord injury (SCI). A single acute SCI subject who was followed longitudinally developed potentiation characteristics very similar to the untrained limbs of the training subjects. The results of the present investigation support that postfatigue potentiation is a characteristic of fast-fatigable muscle and can be prevented by timely neuromuscular electrical stimulation training. Potentiation is an important consideration in the design of functional electrical stimulation control systems for people with SCI.

Fundamental and applied biological sciences. Psychology

Biological and medical sciences

Details

Title: Subtitle: Postfatigue potentiation of the paralyzed soleus muscle : evidence for adaptation with long-term electrical stimulation training
Creators: Richard K SHIELDS - Graduate Program in Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, Iowa, United States
Shauna DUDLEY-JAVOROSKI - Graduate Program in Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, Iowa, United States
Andrew E LITTMANN - Graduate Program in Physical Therapy and Rehabilitation Science, The University of Iowa, Iowa City, Iowa, United States
Resource Type: Journal article
Publication Details: Journal of applied physiology (1985), Vol.101(2), pp.556-565
DOI: 10.1152/japplphysiol.00099.2006
PMID: 16575026
PMCID: PMC3270308
NLM abbreviation: J Appl Physiol (1985)
ISSN: 8750-7587
eISSN: 1522-1601
Publisher: American Physiological Society; Bethesda, MD
Language: English
Date published: 2006
Academic Unit: Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
Record Identifier: 9984047716402771

Metrics

18 Record Views

31 Times Cited - Web of Science