Journal article
Postmortem Diagnosis of Autochthonous Acute Chagasic Myocarditis by Polymerase Chain Reaction Amplification of a Species-Specific DNA Sequence of Trypanosoma cruzi
The American journal of tropical medicine and hygiene, Vol.54(5), pp.526-529
05/01/1996
DOI: 10.4269/ajtmh.1996.54.526
PMID: 8644910
Abstract
We report a fatal case of vector-transmitted acute Chagas' myocarditis in a seven-month-old child in south Texas. This diagnosis was not suspected during the three days of hospitalization that preceded the child's death, which was caused by heart failure. A diagnosis of acute myocarditis, probably of viral origin, was listed as the cause of death after cardiac tissue was examined microscopically at autopsy. One year after the death of the patient, a diagnosis of Trypanosoma cruzi myocarditis, based solely on morphological grounds, was made after newly prepared slides of cardiac tissue were examined. Seven years later, we confirmed the diagnosis of T. cruzi infection by using the polymerase chain reaction to amplify a species-specific genomic repetitive DNA sequence of the parasite from fixed cardiac tissue.
Details
- Title: Subtitle
- Postmortem Diagnosis of Autochthonous Acute Chagasic Myocarditis by Polymerase Chain Reaction Amplification of a Species-Specific DNA Sequence of Trypanosoma cruzi
- Creators
- Diane E. Ochs - University of IowaJerome H. SmithDavid R. MoserViolette S. HnilicaLouis V. Kirchhoff
- Resource Type
- Journal article
- Publication Details
- The American journal of tropical medicine and hygiene, Vol.54(5), pp.526-529
- DOI
- 10.4269/ajtmh.1996.54.526
- PMID
- 8644910
- ISSN
- 0002-9637
- eISSN
- 1476-1645
- Language
- English
- Date published
- 05/01/1996
- Academic Unit
- Psychiatry; Infectious Diseases; Epidemiology; Internal Medicine
- Record Identifier
- 9984280873302771
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