Journal article
Postprandial Triglycerides Across the Aging Spectrum: A Secondary Analysis Utilizing an Abbreviated Fat Tolerance Test
Nutrition, metabolism, and cardiovascular diseases, Vol.34(1), pp.121-125
01/2024
DOI: 10.1016/j.numecd.2023.08.017
PMID: 37788958
Abstract
Background & Aims
Elevated postprandial triglycerides are an independent cardiovascular disease risk factor and observed in older adults. However, differences in postprandial triglycerides across the spectrum of adulthood remain unclear.
Methods and Results
We performed a secondary analysis of six studies where adults (aged 18-84 years; N=155) completed an abbreviated fat tolerance test (9 kcal/kg;70% fat). Differences in postprandial triglycerides were compared in those >50 and <50 years and by decade of life, adjusting for sex and BMI. Compared to those <50 years, participants >50 years had higher fasting, 4-hour, and Δ triglycerides from baseline (p’s<0.05). When examining triglyceride parameters by decade, no differences were observed for fasting triglycerides, but 50s, 60s, and 70s-80s displayed greater 4-hour and Δ triglycerides versus 20s (p’s<0.001). The frequency of adverse postprandial triglyceride responses (i.e., >220 mg/dL) was higher in participants >50 versus <50 years (p<0.01), and in 60s compared to all other decades (p=0.01).
Conclusion
Older age was generally associated with higher postprandial triglycerides, with no divergence across the spectrum of older adulthood. In our sample, postprandial triglyceride differences in older and younger adults were driven by those >50 years relative to young adults in their 20s.
Details
- Title: Subtitle
- Postprandial Triglycerides Across the Aging Spectrum: A Secondary Analysis Utilizing an Abbreviated Fat Tolerance Test
- Creators
- Bryant H. KeirnsChristina M. SciarrilloKara L. PoindexterMadison D. DixonAustin R. MedlinNicholas A. KoemelSamantha M. HartCaroline H. GeistNathaniel D.M. JenkinsEdralin A. LucasSam R. Emerson
- Resource Type
- Journal article
- Publication Details
- Nutrition, metabolism, and cardiovascular diseases, Vol.34(1), pp.121-125
- DOI
- 10.1016/j.numecd.2023.08.017
- PMID
- 37788958
- NLM abbreviation
- Nutr Metab Cardiovasc Dis
- ISSN
- 0939-4753
- eISSN
- 1590-3729
- Grant note
- DOI: 10.13039/100008569, name: Oklahoma Center for the Advancement of Science and Technology
- Language
- English
- Electronic publication date
- 08/2023
- Date published
- 01/2024
- Academic Unit
- Center for Social Science Innovation; Injury Prevention Research Center; Health, Sport, and Human Physiology
- Record Identifier
- 9984459656502771
Metrics
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