Journal article
Postprocedure protocols after intraarticular orthobiologic injections-A scoping review
PM & R, Vol.17(4), pp.463-468
04/2025
DOI: 10.1002/pmrj.13271
PMCID: PMC11974486
PMID: 39382011
Appears in UI Libraries Support Open Access
Abstract
Osteoarthritis is a chronic degenerative disease affecting 500 million people throughout the world. Although orthobiologics have been proposed as a symptom and disease modifying treatment for osteoarthritis, there is significant heterogeneity in the results of the orthobiologic procedures in the literature. One possible explanation for the heterogeneity is the inconsistent reporting and description of the postorthobiologic protocols. The goal of this scoping review was to identify the current literature on the use of orthobiologics for osteoarthritis and critically evaluate the postorthobiologic protocol within these studies. A total of 200 identified studies met inclusion criteria. In 37.5% of studies, there was no mention of a postorthobiologic protocol. Of the 125 studies that did mention a postorthobiologic protocol, only 38.4% included a rehabilitation protocol, 21.6% included postprocedure weightbearing restrictions, and only 2 (1.6%) mentioned the use of durable medical equipment. Nonsteroidal anti-inflammatory drug restriction was described in 91.2% of study protocols, whereas corticosteroids and immunosuppressants were restricted in 84.8% and 19.2% of protocols, respectively. The results of this scoping review demonstrate the inconsistent reporting of postorthobiologic procedure protocols in the literature, with significant heterogeneity in those that are described. These findings highlight the need for future research and improved reporting of postorthobiologic protocols.
Details
- Title: Subtitle
- Postprocedure protocols after intraarticular orthobiologic injections-A scoping review
- Creators
- Ryan C Kruse - University of IowaKristina D Rossmiller - University of IowaTimothy R Fleagle - Department of Physical Therapy and Rehabilitation Sciences, University of Iowa, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- PM & R, Vol.17(4), pp.463-468
- DOI
- 10.1002/pmrj.13271
- PMID
- 39382011
- PMCID
- PMC11974486
- NLM abbreviation
- PM R
- ISSN
- 1934-1563
- eISSN
- 1934-1563
- Publisher
- Wiley
- Grant note
Jen Deberg for her excellent support with the literature search.
- Language
- English
- Electronic publication date
- 10/09/2024
- Date published
- 04/2025
- Academic Unit
- Orthopedics and Rehabilitation
- Record Identifier
- 9984722561202771
Metrics
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