Journal article
Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
Lancet neurology, Vol.11(1), pp.42-53
2012
DOI: 10.1016/S1474-4422(11)70263-0
PMID: 22137354
Abstract
TRACK-HD is a prospective observational biomarker study in premanifest and early Huntington's disease (HD). In this report we define a battery of potential outcome measures for therapeutic trials.
Details
- Title: Subtitle
- Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
- Creators
- Sarah J Tabrizi - UCL Institute of Neurology, University College London, Queen Square, London, UKRalf Reilmann - Department of Neurology, University of Münster, Münster, GermanyRaymund AC Roos - Department of Neurology, Leiden University Medical Centre, Leiden, NetherlandsAlexandra Durr - Department of Genetics and Cytogenetics, and INSERM UMR S679, APHP Hôpital de la Salpêtrière, Paris, FranceBlair Leavitt - Department of Medical Genetics, University of British Columbia, Vancouver, BC, CanadaGail Owen - UCL Institute of Neurology, University College London, Queen Square, London, UKRebecca Jones - Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UKHans Johnson - Department of Psychiatry, University of Iowa, Iowa City, IA, USADavid Craufurd - Genetic Medicine, University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, St Mary's Hospital, Manchester, UKStephen L Hicks - Department of Clinical Neurology, University of Oxford, Oxford, UKChristopher Kennard - Department of Clinical Neurology, University of Oxford, Oxford, UKBernhard Landwehrmeyer - Department of Neurology, Ulm University, Ulm, GermanyJulie C Stout - School of Psychology and Psychiatry, Monash University, VIC, AustraliaBeth Borowsky - CHDI/HighQ Foundation Inc, New York, NY, USARachael I Scahill - UCL Institute of Neurology, University College London, Queen Square, London, UKChris Frost - Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UKDouglas R Langbehn - Departments of Psychiatry and Biostatistics, University of Iowa, Iowa City, IA, USATRACK-HD investigators
- Resource Type
- Journal article
- Publication Details
- Lancet neurology, Vol.11(1), pp.42-53
- DOI
- 10.1016/S1474-4422(11)70263-0
- PMID
- 22137354
- NLM abbreviation
- Lancet Neurol
- ISSN
- 1474-4422
- eISSN
- 1474-4465
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 2012
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Psychiatry; Iowa Neuroscience Institute
- Record Identifier
- 9984003989002771
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