Journal article
Preconceptional folic acid-containing supplement use in the national birth defects prevention study: Preconceptional Folic Acid Supplementation
Birth defects research. A Clinical and molecular teratology, Vol.100(6), pp.472-482
06/2014
DOI: 10.1002/bdra.23238
PMID: 24706436
Abstract
Background: Despite public health campaigns encouraging women to take a daily folic acid supplement, the proportion of reproductive age women, in the United States, who comply with this recommendation is less than optimal. The objective of this analysis was to identify predictors of preconceptional folic acid-containing supplement use to define subgroups of women who may benefit from targeted folic acid campaigns. Methods: This study included 6570 mothers of live born infants from the control population of National Birth Defects Prevention Study (1997–2005). Logistic regression analyses were used to identify predictors of preconceptional folic acid supplementation. A classification and regression tree (CART) analysis was used to define subgroups of women with different patterns of preconceptional folic acid supplementation. Results: Race/ethnicity, education, age at delivery, nativity, employment, income, number of dependents, smoking, and birth control use were significantly associated with preconceptional folic acid-containing supplement use. Based on a CART analysis, education, race/ethnicity, and age were the most distinguishing factors between women with different preconceptional supplementation patterns. Non-white women with <4 years of a college education were the least likely to use folic acid-containing supplements (11%). However, even in the most compliant subgroup (women with ≥4 years of college), only 60% of women supplemented with folic acid. Conclusion: These results demonstrate the need for continued efforts to increase folic acid supplementation among all reproductive aged women. However, the success of such efforts may be improved if maternal characteristics such as education, race/ethnicity, and age, are considered in the development of future interventions.
Details
- Title: Subtitle
- Preconceptional folic acid-containing supplement use in the national birth defects prevention study: Preconceptional Folic Acid Supplementation
- Creators
- Zeina G Khodr - Division of Epidemiology, Human Genetics and Environmental Sciences; University of Texas School of Public Health; Houston TexasPhilip J Lupo - Division of Epidemiology, Human Genetics and Environmental Sciences; University of Texas School of Public Health; Houston Texas, Human Genetics Center; University of Texas School of Public Health; Houston TexasA.J Agopian - Division of Epidemiology, Human Genetics and Environmental Sciences; University of Texas School of Public Health; Houston Texas, Human Genetics Center; University of Texas School of Public Health; Houston TexasMark A Canfield - Birth Defects Epidemiology and Surveillance Branch; Texas Department of State Health Services; Austin TexasAmy P Case - Birth Defects Epidemiology and Surveillance Branch; Texas Department of State Health Services; Austin TexasSuzan L Carmichael - Division of Neonatology, Department of Pediatrics; Stanford University School of Medicine; Stanford CaliforniaLaura E Mitchell - Division of Epidemiology, Human Genetics and Environmental Sciences; University of Texas School of Public Health; Houston Texas, Human Genetics Center; University of Texas School of Public Health; Houston Texas
- Contributors
- Paul A Romitti (Contributor) - University of Iowa, EpidemiologyNational Birth Defects Prevention Study
- Resource Type
- Journal article
- Publication Details
- Birth defects research. A Clinical and molecular teratology, Vol.100(6), pp.472-482
- DOI
- 10.1002/bdra.23238
- PMID
- 24706436
- NLM abbreviation
- Birth Defects Res A Clin Mol Teratol
- ISSN
- 1542-0752
- eISSN
- 1542-0760
- Publisher
- Wiley
- Grant note
- DOI: 10.13039/100000030, name: Centers for Disease Control and Prevention, award: U01DD000494; name: Office of Title V and Family Health, Texas DSHS, award: Title V Maternal and Child Health Block Grants Funds
- Language
- English
- Date published
- 06/2014
- Academic Unit
- Epidemiology; Biostatistics
- Record Identifier
- 9984214712902771
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