Journal article
Prediction of Language and Neurologic Recovery After Cerebral Infarction With SPECT Imaging Using N-Isopropyl-p-(I 123) Iodoamphetamine
Archives of neurology (Chicago), Vol.46(6), pp.665-669
06/01/1989
DOI: 10.1001/archneur.1989.00520420085027
PMID: 2786406
Abstract
• Fourteen patients (10 with left-sided and 4 with right-sided cerebral infarction) were prospectively studied with single-photon emission computed tomography (SPECT) using N-isopropyl-p-(1 123) iodoamphetamine (IMP, SPECTamine) to determine its usefulness in predicting neurologic/language recovery after cerebral infarction. All neuro-SPECT imaging was performed within 30 days after infarction. Detailed assessment of neurologic and/or language recovery (after 3 months) was carried out prospectively in each patient. Patients with smaller volume IMP defects in the region of infarction demonstrated significantly better neurologic and language recovery than patients with large IMP defects. Analysis of the IMP "redistribution" phenomenon failed to demonstrate definitively a relationship with clinical recovery. It was concluded that the volume of the IMP defect can aid in predicting recovery potential after cerebral infarction.
Details
- Title: Subtitle
- Prediction of Language and Neurologic Recovery After Cerebral Infarction With SPECT Imaging Using N-Isopropyl-p-(I 123) Iodoamphetamine
- Creators
- David L Bushnell - United States Department of Veterans AffairsSudha GuptaAnthony G MlcochW. Earl Barnes
- Resource Type
- Journal article
- Publication Details
- Archives of neurology (Chicago), Vol.46(6), pp.665-669
- DOI
- 10.1001/archneur.1989.00520420085027
- PMID
- 2786406
- NLM abbreviation
- Arch Neurol
- ISSN
- 0003-9942
- eISSN
- 1538-3687
- Publisher
- American Medical Association
- Language
- English
- Date published
- 06/01/1989
- Academic Unit
- Radiology
- Record Identifier
- 9984318808602771
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