Predictive model of muscle fatigue after spinal cord injury in humans

Richard K Shields; Ya-Ju Chang; Shauna Dudley-Javoroski; Cheng-Hsiang Lin

doi:10.1002/mus.20564

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Predictive model of muscle fatigue after spinal cord injury in humans

Journal article

Peer reviewed

Predictive model of muscle fatigue after spinal cord injury in humans

Richard K Shields, Ya-Ju Chang, Shauna Dudley-Javoroski and Cheng-Hsiang Lin

Muscle & nerve, Vol.34(1), pp.84-91

07/2006

DOI: 10.1002/mus.20564

PMCID: PMC3272267

PMID: 16634064

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Abstract

The fatigability of paralyzed muscle limits its ability to deliver physiological loads to paralyzed extremities during repetitive electrical stimulation. The purposes of this study were to determine the reliability of measuring paralyzed muscle fatigue and to develop a model to predict the temporal changes in muscle fatigue that occur after spinal cord injury (SCI). Thirty-four subjects underwent soleus fatigue testing with a modified Burke electrical stimulation fatigue protocol. The between-day reliability of this protocol was high (intraclass correlation, 0.96). We fit the fatigue index (FI) data to a quadratic-linear segmental polynomial model. FI declined rapidly (0.3854 per year) for the first 1.7 years, and more slowly (0.01 per year) thereafter. The rapid decline of FI immediately after SCI implies that a "window of opportunity" exists for the clinician if the goal is to prevent these changes. Understanding the timing of change in muscle endurance properties (and, therefore, load-generating capacity) after SCI may assist clinicians when developing therapeutic interventions to maintain musculoskeletal integrity.

Predictive Value of Tests

Reproducibility of Results

Humans

Middle Aged

Male

Tibial Nerve - radiation effects

Regression Analysis

Tibial Nerve - physiopathology

Analysis of Variance

Time Factors

Models, Biological

Muscle, Skeletal - radiation effects

Muscle, Skeletal - physiopathology

Adolescent

Adult

Female

Spinal Cord Injuries - physiopathology

Muscle Fatigue - physiology

Electric Stimulation - methods

Details

Title: Subtitle: Predictive model of muscle fatigue after spinal cord injury in humans
Creators: Richard K Shields - Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, 1-252 MEB, Iowa City, Iowa 52240-1190, USA. Richard-Shields@uiowa.edu
Ya-Ju Chang
Shauna Dudley-Javoroski
Cheng-Hsiang Lin
Resource Type: Journal article
Publication Details: Muscle & nerve, Vol.34(1), pp.84-91
DOI: 10.1002/mus.20564
PMID: 16634064
PMCID: PMC3272267
NLM abbreviation: Muscle Nerve
ISSN: 0148-639X
eISSN: 1097-4598
Publisher: United States
Grant note: R01 HD039445 / NICHD NIH HHS R01-HD 39445 / NICHD NIH HHS R01 HD039445-04 / NICHD NIH HHS
Language: English
Date published: 07/2006
Academic Unit: Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
Record Identifier: 9984047659702771

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