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Predictors of Early Extubation after Patent Ductus Arteriosus Ligation among Infants Born Extremely Preterm Dependent on Mechanical Ventilation
Journal article   Peer reviewed

Predictors of Early Extubation after Patent Ductus Arteriosus Ligation among Infants Born Extremely Preterm Dependent on Mechanical Ventilation

Srinath Krishnappa, Prakesh S Shah, Amish Jain, Maura H.F Resende, Patrick J McNamara and Dany E Weisz
The Journal of pediatrics, Vol.214, pp.222-226.e3
11/2019
DOI: 10.1016/j.jpeds.2019.06.027
PMID: 31279574

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Abstract

We conducted a retrospective study of 166 ventilator-dependent neonates born extremely preterm in whom patent ductus arteriosus was surgically ligated and evaluated the association of preoperative characteristics and time-to-successful postoperative extubation. Larger patent ductus arteriosus diameter ([>2.5 mm], adjusted hazard ratio 0.51, 95% CI 0.36-0.72) and left-ventricular dilatation (z score ≥2, adjusted hazard ratio 0.61, 95% CI 0.42-0.87) were associated with earlier extubation.
pressure gradient extremely low gestational age peak systolic velocity ductal shunt volume ductal diameter PDA surgery successful extubation PDA left ventricular dilatation

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