Journal article
Predictors of aneurysm occlusion following treatment with the WEB device: systematic review and case series
Neurosurgical review, Vol.45(2), pp.925-936
04/01/2022
DOI: 10.1007/s10143-021-01638-7
PMID: 34480649
Abstract
The Woven EndoBridge (WEB) device is becoming increasingly popular for treatment of wide-neck aneurysms. As experience with this device grows, it is important to identify factors associated with occlusion following WEB treatment to guide decision making and screen patients at high risk for recurrence. The aim of this study was to identify factors associated with adequate aneurysm occlusion following WEB device treatment in the neurosurgical literature and in our case series. A systematic review of the present literature was conducted to identify studies related to the prediction of WEB device occlusion. In addition, a retrospective review of our institutional data for patients treated with the WEB device was performed. Demographics, aneurysm characteristics, procedural variables, and 6-month follow-up angiographic outcomes were recorded. Seven articles totaling 450 patients with 456 aneurysms fit our criteria. Factors in the literature associated with inadequate occlusion included larger size, increased neck width, partial intrasaccular thrombosis, irregular shape, and tobacco use. Our retrospective review identified 43 patients with 45 aneurysms. A total of 91.1% of our patients achieved adequate occlusion at a mean follow-up time of 7.32 months. Increasing degree of contrast stasis after WEB placement on the post-deployment angiogram was significantly associated with adequate occlusion on follow-up angiogram (p = 0.005) and with Raymond-Roy classification (p = 0.048), but not with retreatment (p = 0.617). In our systematic review and case series totaling 450 patients with 456 aneurysms, contrast stasis on post-deployment angiogram was identified as a predictor of adequate aneurysm occlusion, while morphological characteristics such as larger size and wide neck negatively impact occlusion.
Details
- Title: Subtitle
- Predictors of aneurysm occlusion following treatment with the WEB device: systematic review and case series
- Creators
- Fadi Al Saiegh - Thomas Jefferson UniversityLohit Velagapudi - Thomas Jefferson UniversityOmaditya Khanna - Thomas Jefferson UniversityAhmad Sweid - Thomas Jefferson UniversityNikolaos Mouchtouris - Thomas Jefferson UniversityMichael P. Baldassari - Thomas Jefferson UniversityThana Theofanis - Thomas Jefferson UniversityRizwan Tahir - Thomas Jefferson UniversityVictoria Schunemann - Thomas Jefferson UniversityCarrie Andrews - Thomas Jefferson UniversityLucas Philipp - Thomas Jefferson UniversityNohra Chalouhi - University of FloridaStavropoula Tjoumakaris - Thomas Jefferson UniversityDavid Hasan - University of IowaM. Reid Gooch - Thomas Jefferson UniversityNabeel A. Herial - Thomas Jefferson UniversityRobert H. Rosenwasser - Thomas Jefferson UniversityPascal Jabbour - Thomas Jefferson University
- Resource Type
- Journal article
- Publication Details
- Neurosurgical review, Vol.45(2), pp.925-936
- Publisher
- Springer Nature
- DOI
- 10.1007/s10143-021-01638-7
- PMID
- 34480649
- ISSN
- 0344-5607
- eISSN
- 1437-2320
- Number of pages
- 12
- Language
- English
- Date published
- 04/01/2022
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984419235602771
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