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Predictors of angiographic occlusion after embolization of intracranial arteriovenous malformations with curative intent
Journal article   Open access   Peer reviewed

Predictors of angiographic occlusion after embolization of intracranial arteriovenous malformations with curative intent

Joanna M Roy, Basel Musmar, Shyam Majmundar, Anand Kaul, Elias Atallah, Mario Zanaty, Saman Sizdahkhani, Nikolaos Mouchtouris, Panagiotis Mastorakos, Stavropoula I Tjoumakaris, …
Interventional neuroradiology
04/15/2025
DOI: 10.1177/15910199251332400
PMCID: PMC11999980
PMID: 40232292
url
https://www.ncbi.nlm.nih.gov/pmc/articles/11999980View
Open Access

Abstract

Background Endovascular embolization is a potential alternative to open surgery for treating intracranial arteriovenous malformations (AVMs). To our knowledge, predictors of occlusion after curative embolization of AVMs remain limited in literature. Our study aims to identify predictors of radiographic occlusion after embolization of AVMs with curative intent. Methods This was a retrospective study of patients who underwent embolization of AVMs with curative intent at a single institution between 2007 and 2022. The primary outcome of cure was defined as radiographic occlusion of the AVM on follow-up. Univariate and multivariate analyses were performed with a P value <0.05 denoting statistical significance. Results Sixty-six patients underwent embolization of an AVM with curative intent. The median (interquartile range (IQR)) age of the cohort was 53 (36–62), and 48.5% were male. 65.2% (n = 43) patients presented with hemorrhage. 59.1% (n = 39) of the cohort achieved cure on follow-up. Median (IQR) volume of AVM (mm3) and maximum pedicle size (mm) were significantly higher in patients who were not cured on follow-up compared to those who were cured: 14055.12 (2431.71–31235.60) and 1.9 (1.3–2.5) versus 3888 (2063–12518) and 1.3 (1.1–1.6), respectively. On multivariate regression, maximum pedicle size was associated with lower odds of cure (OR: 0.24, 95% CI: 0.07–0.82, P = 0.023). Conclusions Our study identified maximum pedicle size to be the only significant factor associated with lower odds of radiographic occlusion after curative embolization of AVMs. Further multicenter studies are required to validate these findings.
 endovascular embolization angiographic occlusion Arteriovenous malformation

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