Journal article
Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy-US Territories, January 1, 2016-April 25, 2017
MMWR. Morbidity and mortality weekly report, Vol.66(23), pp.615-621
06/16/2017
DOI: 10.15585/mmwr.mm6623e1
PMCID: PMC5657842
PMID: 28617773
Abstract
Summary
What is already known about this topic?
Zika virus infection during pregnancy causes serious brain abnormalities and/or microcephaly and has been associated with other severe birth defects. Local transmission of Zika virus was reported in U.S. territories in 2016.
What is added by this report?
Overall, about 5% of fetuses and infants born to women with laboratory evidence of recent possible Zika virus infection in the U.S. territories had possible Zika-associated birth defects, the same as the percentage reported in the 50 U.S. states during 2016. Possible Zika-associated birth defects including brain abnormalities and/or microcephaly were reported following Zika virus infection during every trimester of pregnancy. Among completed pregnancies with positive nucleic acid tests confirming Zika virus infection identified in the first, second, and third trimesters, the percentages of fetuses or infants with possible Zika-associated birth defects was 8%, 5%, and 4%, respectively.
What are the implications for public health practice?
Current data suggest that Zika virus infection during any trimester of pregnancy might result in Zika-associated birth defects. Identification and follow-up of infants born to women with laboratory evidence of recent possible Zika virus infection during pregnancy can facilitate timely and appropriate clinical intervention services and assessment of future needs. Information about adherence to the recommended newborn testing and screening can improve monitoring and care of infants affected by Zika.
Details
- Title: Subtitle
- Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy-US Territories, January 1, 2016-April 25, 2017
- Creators
- Carrie K. Shapiro-Mendoza - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USAMarion E. Rice - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USARomeo R. Galang - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAAnna C. Fulton - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAKelley VanMaldeghem - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAMiguel Valencia Prado - Puerto Rico Dept Hlth, Ponce, PR USAEsther Ellis - US Virgin Isl Dept Hlth, St Thomas, VI USAMagele Scott Anesi - Amer Samoa Dept Hlth, Pago Pago, AS USARegina M. Simeone - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAEmily E. Petersen - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USASascha R. Ellington - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USAAbbey M. Jones - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USATonya Williams - CDC, Div Human Dev & Disabil, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USASarah Reagan-Steiner - CDC, Div High Consequence Pathogens & Pathol, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USAJanice Perez-Padilla - National Center for Emerging and Zoonotic Infectious DiseasesCarmen C. Deseda - Puerto Rico Dept Hlth, Ponce, PR USAAndrew Beron - US Virgin Isl Dept Hlth, St Thomas, VI USAAifili John TufaAsher Rosinger - CDC, Epidem Intelligence Serv, Atlanta, GA 30333 USANicole M. Roth - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USACaitlin Green - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAStacey Martin - National Center for Emerging and Zoonotic Infectious DiseasesCamille Delgado Lopez - Puerto Rico Dept Hlth, Ponce, PR USALeah deWilde - US Virgin Isl Dept Hlth, St Thomas, VI USAMary Goodwin - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USAH. Pamela Pagano - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USACara T. Mai - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USACarolyn Gould - National Center for Emerging and Zoonotic Infectious DiseasesSherif Zaki - CDC, Div High Consequence Pathogens & Pathol, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USALeishla Nieves Ferrer - Puerto Rico Dept Hlth, Ponce, PR USAMichelle S. Davis - US Virgin Isl Dept Hlth, St Thomas, VI USAEva Lathrop - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAKara Polen - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAJanet D. Cragan - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAMegan Reynolds - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAKimberly B. Newsome - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USAMariam Marcano Huertas - Puerto Rico Dept Hlth, Ponce, PR USAJulu Bhatangar - CDC, Div High Consequence Pathogens & Pathol, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USAAlma Martinez Quinones - Puerto Rico Dept Hlth, Ponce, PR USAJohn F. Nahabedian - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USALaura Adams - National Center for Emerging and Zoonotic Infectious DiseasesTyler M. Sharp - National Center for Emerging and Zoonotic Infectious DiseasesW. Thane Hancock - Centers for Disease Control and PreventionSonja A. Rasmussen - Ctr Surveillance Epidemiol & Lab Serv, Div Publ Hlth Informat Disseminat, Atlanta, GA USACynthia A. Moore - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USADenise J. Jamieson - CDC, Div Reprod Hlth, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA 30333 USAJorge L. Munoz-Jordan - National Center for Emerging and Zoonotic Infectious DiseasesHelentina Garstang - Republ Marshall Isl Minist Hlth, Majuro, Marshall IslandAfeke Kambui - Wrexham UniversityCarolee Masao - Kosrae Dept Hlth Serv, Kosrae, MicronesiaMargaret A. Honein - CDC, Div Congenital & Dev Disorders, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30333 USADana Meaney-Delman - CDC, Off Director, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30333 USAZika Pregnancy and Infant Registries Working Group
- Resource Type
- Journal article
- Publication Details
- MMWR. Morbidity and mortality weekly report, Vol.66(23), pp.615-621
- Publisher
- CENTERS DISEASE CONTROL
- DOI
- 10.15585/mmwr.mm6623e1
- PMID
- 28617773
- PMCID
- PMC5657842
- ISSN
- 0149-2195
- eISSN
- 1545-861X
- Number of pages
- 7
- Language
- English
- Date published
- 06/16/2017
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446556402771
Metrics
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